Matteri R L, Moberg G P
J Endocrinol. 1982 Jan;92(1):141-6. doi: 10.1677/joe.0.0920141.
During treatment with cortisol or ACTH, dairy heifers were given two doses of LH releasing hormone (LH-RH) spaced 1.5 h apart. Serum concentrations of cortisol and LH were monitored during each treatment. Treatment with both ACTH and cortisol raised plasma cortisol levels above the respective saline controls (P less than 0.001). Neither treatment affected basal LH concentrations. A slight depression in LH response was seen in the cortisol-treated animals after the first LH-RH injection, as shown by a statistically significant depression at three of the sample times. There was no significant difference between treated and control LH values after the second LH-RH administration. Treatment with ACTH resulted in significantly reduced LH values at all sample times after both injections of LH-RH.
在用皮质醇或促肾上腺皮质激素(ACTH)治疗期间,给奶牛小母牛间隔1.5小时注射两剂促黄体生成素释放激素(LH-RH)。在每次治疗期间监测皮质醇和LH的血清浓度。ACTH和皮质醇治疗均使血浆皮质醇水平高于各自的生理盐水对照组(P<0.001)。两种治疗均未影响基础LH浓度。在第一次注射LH-RH后,皮质醇治疗的动物中LH反应略有下降,在三个采样时间点有统计学意义的下降。第二次注射LH-RH后,治疗组和对照组的LH值无显著差异。ACTH治疗导致在两次注射LH-RH后的所有采样时间点LH值均显著降低。