Department of Rehabilitation Medicine, Lianshui County People's Hospital, Huai'an, Jiangsu 223400, China.
Department of Rehabilitation Medicine, The Affiliated Huai'an Hospital of Xuzhou Medical University (Huai'an Second People's Hospital), Huai'an, Jiangsu 223002, China.
Comput Math Methods Med. 2022 Sep 26;2022:1822262. doi: 10.1155/2022/1822262. eCollection 2022.
To investigate the clinical efficacy of ultrasound (US) combined with neuromuscular electrical stimulation (NMES) in treating lumbar disc herniation (LDH) and its effect on the level of inflammatory factors.
The data of 240 patients with LDH treated at our hospital from January 2020 to February 2021 were reviewed and classified into an US combined with NMES treatment group (US+NMES, = 80), NMES only treatment group (NMES, = 80), and US only treatment group (US, = 80). Their Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) scores, levels of inflammatory factors and pain mediators, recovery rate, and total recovery time before and after treatment were compared. Additionally, the incidence of complications/adverse reactions was also investigated.
Compared with data before treatment, the three groups had lower VAS and ODI scores, inflammatory factor levels (interleukin- [IL-] 1, IL-6, and tumor necrosis factor- [TNF-] ), and pain mediators (transforming growth factor- [TGF-] 1, prostaglandin E2 [PEG2], and 5-hydroxytryptamine [5-HT]) after treatment, with the most significant decrease observed in the US+NMES group. Compared with patients who received US or NMES treatment alone, patients from the US+NMES had faster recovery time and lower incidence of complications/adverse reactions.
Collectively, US combined with NMES was associated with significant relief in pain and lumbar dysfunction and reduced local inflammatory response and pain mediator levels in LDH patients, suggesting that this combined approach could achieve better efficacy than US or NMES alone.
探究超声（US）联合神经肌肉电刺激（NMES）治疗腰椎间盘突出症（LDH）的临床疗效及其对炎症因子水平的影响。
回顾性分析 2020 年 1 月至 2021 年 2 月我院收治的 240 例 LDH 患者的临床资料，将其分为超声联合神经肌肉电刺激治疗组（US+NMES 组，n=80）、单纯神经肌肉电刺激治疗组（NMES 组，n=80）和单纯超声治疗组（US 组，n=80）。比较三组患者治疗前后视觉模拟评分（VAS）和 Oswestry 功能障碍指数（ODI）评分、炎症因子和疼痛介质水平、恢复率及总康复时间，同时观察三组患者并发症/不良反应发生率。
与治疗前相比，三组患者 VAS 和 ODI 评分、炎症因子水平（白细胞介素-1、白细胞介素-6、肿瘤坏死因子-α）和疼痛介质水平（转化生长因子-β1、前列腺素 E2、5-羟色胺）均降低，其中 US+NMES 组降低幅度最大。与 US 组或 NMES 组比较，US+NMES 组患者康复时间更短，并发症/不良反应发生率更低。
US 联合 NMES 可明显缓解 LDH 患者的疼痛和腰部功能障碍，减轻局部炎症反应和疼痛介质水平，疗效优于单纯 US 或 NMES 治疗。
