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使用……生物合成的银纳米颗粒的优化、表征及抗癌潜力

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using .

作者信息

Felimban Afnan I, Alharbi Njud S, Alsubhi Nehad S

机构信息

Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Department of Biological Science, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.

出版信息

Int J Biomater. 2022 Sep 26;2022:6859637. doi: 10.1155/2022/6859637. eCollection 2022.

DOI:10.1155/2022/6859637
PMID:36199851
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9529486/
Abstract

Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using extracts and evaluated their anticancer potential. The biosynthesized AgNPs were characterized using various methods, showing stable AgNPs with a desirable morphology and high yield, improving the properties of AgNPs for various medicinal applications. The biosynthesized AgNPs were predominantly spherical, with small sizes ranging from 13 to 21 nm and highly stable at -23 and -24 mV. The findings of this study suggest that green-synthesized AgNPs using and sunlight possess significant anticancer activity against cancer cells . Further investigation of green synthesis would help to form high-quality AgNPs that have promising potential in treating disease and fighting undesirable pathogens.

摘要

作为一种用于癌症治疗的制备银纳米颗粒(AgNPs)的环保、低成本、节能且无毒的方法,绿色合成已引起了广泛关注。本研究优化了使用提取物进行AgNPs的绿色合成,并评估了它们的抗癌潜力。采用多种方法对生物合成的AgNPs进行了表征,结果表明所得到的AgNPs形态理想、产量高且稳定性好,改善了AgNPs在各种医学应用中的性能。生物合成的AgNPs主要呈球形,尺寸较小,范围为13至21纳米,在-23和-24毫伏时具有高度稳定性。本研究结果表明,利用[提取物名称]和阳光进行绿色合成的AgNPs对癌细胞具有显著的抗癌活性。对绿色合成的进一步研究将有助于制备出高质量的AgNPs,其在治疗疾病和对抗有害病原体方面具有广阔的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/54cae42c2882/IJBM2022-6859637.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/1ac57fe0fc00/IJBM2022-6859637.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/5300625d1457/IJBM2022-6859637.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/6a3202e9afcb/IJBM2022-6859637.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/a813763de04f/IJBM2022-6859637.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/c6c962975c94/IJBM2022-6859637.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/6cd5f4121bfc/IJBM2022-6859637.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/7275bccc4090/IJBM2022-6859637.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/be6359f1eb45/IJBM2022-6859637.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/9ddceb792217/IJBM2022-6859637.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/54cae42c2882/IJBM2022-6859637.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/1ac57fe0fc00/IJBM2022-6859637.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/5300625d1457/IJBM2022-6859637.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/6a3202e9afcb/IJBM2022-6859637.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/a813763de04f/IJBM2022-6859637.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/c6c962975c94/IJBM2022-6859637.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/6cd5f4121bfc/IJBM2022-6859637.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/7275bccc4090/IJBM2022-6859637.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/be6359f1eb45/IJBM2022-6859637.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/9ddceb792217/IJBM2022-6859637.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65dc/9529486/54cae42c2882/IJBM2022-6859637.010.jpg

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