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源自牙源性感染的罕见全身性破伤风:一例病例报告及近期文献综述

Unusual generalized tetanus evolving from odontogenic infection: A case report and review of recent literature.

作者信息

Akbar Muhammad, Ruslin Muhammad, Yusuf Andi Sitti Hajrah, Boffano Paolo, Tomihara Kei, Forouzanfar Tymour

机构信息

Department of Neurology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.

出版信息

Heliyon. 2022 Sep 28;8(9):e10810. doi: 10.1016/j.heliyon.2022.e10810. eCollection 2022 Sep.

Abstract

Tetanus is an acute and vaccine-preventable disease caused by anaerobic bacteria, . This bacterium can enter the human body via a deep wound, burn injury or medical procedure; however, certain cases also originate from odontogenic infection. In the present study, a tetanus infection associated with dental origin in a 44-year-old man is reported. The case was complicated by lockjaw and difficulty swallowing that worsened over a few days, followed by a generalized spasm. Furthermore, a literature review was performed, in which six reported cases of tetanus, presumed to be of dental or oral origin, were identified between 2011and 2021. General practitioners, especially dentists, should be aware of tetanus associated with odontogenic origin even without a history of an external penetrating wound or other medical procedures:.

摘要

破伤风是一种由厌氧菌引起的急性且可通过疫苗预防的疾病。这种细菌可通过深部伤口、烧伤或医疗操作进入人体;然而,某些病例也源于牙源性感染。在本研究中,报告了一名44岁男性的牙源性破伤风感染病例。该病例并发牙关紧闭和吞咽困难,在数天内加重,随后出现全身痉挛。此外,还进行了文献综述,在2011年至2021年期间确定了6例据推测为牙源性或口腔源性的破伤风报告病例。全科医生,尤其是牙医,即使没有外部穿透性伤口或其他医疗操作史,也应意识到牙源性破伤风。

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