应关注儿童不明病因的急性肝炎。
Attention should be paid to acute hepatitis of unknown etiology in children.
作者信息
Chen Guangbin, Lu Hongzhou
机构信息
Department of Pharmacy, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
出版信息
Intractable Rare Dis Res. 2022 Aug;11(3):153-157. doi: 10.5582/irdr.2022.01069.
Since April 5, 2022, an increase in cases of severe acute hepatitis of unknown etiology among children with no underlying conditions was first reported in the United Kingdom (UK). Testing excluded viral hepatitis types A, B, C, D, and E and other known common and uncommon infectious and non-infectious causes of acute hepatitis. As of May 26, 2022, 650 cases of acute hepatitis of unknown etiology in children have been reported in at least 33 countries worldwide, with 99 additional cases pending classification. Here, the current prevalence of this condition around the world, a hazard analysis, possible causes, the risk of an outbreak in China, and advice on prevention have been briefly reviewed.
自2022年4月5日起，英国首次报告无基础疾病儿童中出现病因不明的严重急性肝炎病例增加。检测排除了甲型、乙型、丙型、丁型和戊型病毒性肝炎以及其他已知的常见和罕见的急性肝炎感染性和非感染性病因。截至2022年5月26日，全球至少33个国家已报告650例儿童病因不明的急性肝炎病例，另有99例病例待分类。在此，简要回顾了这种疾病目前在全球的流行情况、危害分析、可能病因、在中国爆发的风险以及预防建议。
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