Department of Pediatric Dentistry Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Division of Pediatric Pulmonology School of Medicine, Marmara University, Istanbul, Turkey.
Pediatr Pulmonol. 2023 Jan;58(1):246-252. doi: 10.1002/ppul.26191. Epub 2022 Oct 14.
Health-related quality of life (HRQoL) scales are now widely used in children with cystic fibrosis (cwCF) which reflects the course of the disease. In this cross-sectional study, our primary aim was to compare the Pediatric Oral Health-Related Quality of Life (POQL) and Oral Health Score (OHS) between cwCF and healthy group. Our secondary aim was to evaluate the association between Pseudomonas aeruginosa (PA) colonization, pulmonary function test, OHS and POQL in cwCF.
The study population (age ranging 6-14) included 55 cwCF followed at the Marmara University Division of Pediatric Pulmonology compared with 50 healthy peers. A survey consisted of general questions (age, sex, etc.) and the POQL instrument were filled by parents. The decayed, missing, and filled teeth for both primary (dft) and permanent dentition (DMFT) was detected according to WHO criteria. Data like current body mass index (BMI z score), colonization status with PA, predicted value for forced expiratory volume in 1 second (FEV1pp), and any hospitalizations during the previous year were obtained from their medical. Differences between the groups were evaluated using Chi-square and Mann-Whitney U test with a significance level set at 0.05.
There was no significant difference between PA-colonized cwCF and healthy controls in DMFT (p = 0.916). For all domains of POQL (emotional function, social function, role function), scores of cwCF were significantly better than healthy controls (p < 0.05). There were no statistically significant differences between all domains of POQL scores in PA colonized and non-PA colonized cwCF' POQL scores (p > 0.05).
Although POQL scores of cwCF were encouraging, dental caries prevention and regular follow-ups should be taken into consideration.
健康相关生活质量（HRQoL）量表现在已广泛应用于囊性纤维化（cwCF）患儿，反映了疾病的进程。在这项横断面研究中，我们的主要目的是比较囊性纤维化患儿和健康组的儿童口腔健康相关生活质量（POQL）和口腔健康评分（OHS）。我们的次要目的是评估铜绿假单胞菌（PA）定植、肺功能测试、OHS 和 POQL 之间在 cwCF 中的相关性。
研究人群（年龄 6-14 岁）包括 55 例在马尔马拉大学儿科肺病科就诊的 cwCF，与 50 例健康同龄人进行比较。父母填写了一份包含一般问题（年龄、性别等）和 POQL 量表的调查问卷。根据世界卫生组织（WHO）标准，检测了乳牙（dft）和恒牙（DMFT）的龋齿、缺失和填充情况。从他们的医疗记录中获得了当前体重指数（BMI z 评分）、PA 定植情况、预计 1 秒用力呼气量（FEV1pp）值以及前一年的任何住院情况等数据。采用卡方检验和曼-惠特尼 U 检验比较组间差异，显著性水平设为 0.05。
PA 定植的 cwCF 与健康对照组在 DMFT 方面无显著差异（p=0.916）。在 POQL 的所有领域（情感功能、社会功能、角色功能）中，cwCF 的得分均明显优于健康对照组（p<0.05）。在 PA 定植和非 PA 定植的 cwCF 的 POQL 评分的所有领域之间，POQL 评分无统计学差异（p>0.05）。
尽管 cwCF 的 POQL 评分令人鼓舞，但应考虑预防龋齿和定期随访。
