Department of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, KS, USA.
Department of History and Philosophy of Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Support Care Cancer. 2022 Nov;30(11):9647-9657. doi: 10.1007/s00520-022-07378-8. Epub 2022 Oct 6.
The purpose of this study is to identify the amount and scope of knowledge on sleep disturbance in cancer survivors who have lymphedema. The research question investigated was "what are the known sleep disturbances in cancer survivors with lymphedema?"
A literature search was performed on February 15 to March 27, 2021, in four databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) and structure recommended by Arksey and O'Malley. An iterative process of study selection was performed by two reviewers for abstract and full-text review. The Joanna Briggs Institute's critical appraisal tools were used to analyze study quality.
One hundred twenty-one unique references were reviewed, and seven met the inclusion criteria. One article had the primary aim of assessing sleep and noted that the presence of lymphedema did increase the risk for sleep disturbance. Four cross-sectional studies compared sleep quality between cancer survivors with lymphedema and cancer survivors without lymphedema. These studies found that lymphedema is a significant predictor of insomnia and is a risk factor for insomnia. Two randomized control trials compared sleep among breast cancer survivors with lymphedema after an intervention. Sleep improved with a yoga intervention and was unchanged after adding a night-time compression garment.
In this scoping review, breast and gynecological cancer survivors with lymphedema report increased sleep disturbance compared to survivors without lymphedema. Further research is needed to characterize the specific sleep disturbances in cancer survivors with lymphedema for improved screening and treatment.
本研究旨在确定患有淋巴水肿的癌症幸存者中睡眠障碍的知识量和范围。研究问题是“患有淋巴水肿的癌症幸存者的已知睡眠障碍有哪些？”
2021 年 2 月 15 日至 3 月 27 日，我们在四个数据库中进行了文献检索，遵循系统评价和荟萃分析的首选报告项目扩展（PRISMA-ScR）和 Arksey 和 O'Malley 推荐的结构。两名评审员对摘要和全文进行了反复的研究选择。Joanna Briggs 研究所的批判性评估工具用于分析研究质量。
共审查了 121 篇独特的参考文献，其中 7 篇符合纳入标准。有一篇文章的主要目的是评估睡眠，并指出淋巴水肿的存在确实增加了睡眠障碍的风险。四项横断面研究比较了患有淋巴水肿和没有淋巴水肿的癌症幸存者的睡眠质量。这些研究发现，淋巴水肿是失眠的一个显著预测因素，也是失眠的一个危险因素。两项随机对照试验比较了淋巴水肿乳腺癌幸存者在干预后的睡眠情况。瑜伽干预可改善睡眠，夜间加压服则无变化。
在这项范围综述中，患有淋巴水肿的乳腺癌和妇科癌症幸存者报告的睡眠障碍比没有淋巴水肿的幸存者多。需要进一步研究以确定淋巴水肿癌症幸存者的具体睡眠障碍，以改善筛查和治疗。
