Soltanipur Masood, Yarmohammadi Hossein, Abbasvandi Fereshteh, Montazeri Ali, Sheikhi Zahra
Quality of Life Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
ATMP Department, Breast Cancer Research Center, Motamed Cancer Research Institute, ACECR, Tehran, Iran.
Sleep Breath. 2024 Dec 3;29(1):41. doi: 10.1007/s11325-024-03223-w.
Breast cancer survivors (BCSs) tend to have sleep disturbances such as obstructive sleep apnea (OSA). However, limited evidence exists on the role of breast cancer-related lymphedema (BCRL) in sleep disturbances and OSA. Therefore, this study aimed to investigate the quality of sleep (QoS) and OSA risk among women with and without BCRL.
The quality of life (QoL) was evaluated using the SF-12 and EORTC-QLQ C-30 questionnaires, while their sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The STOP-bang questionnaire (SBQ) was utilized to quantify OSA risk. Sleepiness was assessed using the Epworth Sleepiness Scale (ESS). Also, neck and waist circumference and the excessive volume in the affected limb were measured using a tape measure. The statistical analyses were performed using the SPSS 21.0 software.
Seventy-one women with BCRL and 84 BCS without lymphedema were included. The comparison of PSQI, SBQ, ESS, SF-12, and EORTC QLQ-C30 questionnaires exhibited no significant difference between these two groups. The overnight snoring and average neck circumference were significantly higher in the BCRL group than in the control. The BCRL stage significantly correlated with neck circumference and SBQ total score. Additionally, the mean volume difference indicated a significant correlation with the ESS total score and both physical and mental summary components of the SF-12 questionnaire.
The prevalence of sleep disturbances among BCSs with and without BCRL is high. Women with advanced stages of BCRL might be at high risk for OSA. Therefore clinical evaluation of BMI, neck circumference, and, snoring overnight should be emphasized among this population.
乳腺癌幸存者（BCS）往往存在睡眠障碍，如阻塞性睡眠呼吸暂停（OSA）。然而，关于乳腺癌相关淋巴水肿（BCRL）在睡眠障碍和OSA中的作用，现有证据有限。因此，本研究旨在调查有和没有BCRL的女性的睡眠质量（QoS）和OSA风险。
使用SF-12和EORTC-QLQ C-30问卷评估生活质量（QoL），同时使用匹兹堡睡眠质量指数（PSQI）问卷评估其睡眠质量。采用STOP-bang问卷（SBQ）量化OSA风险。使用爱泼华嗜睡量表（ESS）评估嗜睡情况。此外，用卷尺测量颈部和腰围以及患侧肢体的多余容积。使用SPSS 21.0软件进行统计分析。
纳入71例有BCRL的女性和84例无淋巴水肿的BCS。PSQI、SBQ、ESS、SF-12和EORTC QLQ-C30问卷的比较显示，两组之间无显著差异。BCRL组的夜间打鼾和平均颈围显著高于对照组。BCRL分期与颈围和SBQ总分显著相关。此外，平均容积差与ESS总分以及SF-12问卷的身体和精神总结成分均显著相关。
有和没有BCRL的BCS中睡眠障碍的患病率都很高。BCRL晚期的女性可能有较高的OSA风险。因此，应重视对该人群的体重指数、颈围和夜间打鼾进行临床评估。
