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电物理因子治疗压力性损伤的疗效:系统评价。

Effectiveness of electrophysical agents for treating pressure injuries: a systematic review.

机构信息

Postgraduate Program in Rehabilitation Sciences, Federal University of Santa Catarina, Araranguá, SC, Brazil.

Laboratory of Assessment and Rehabilitation of Locomotor System (LARAL), Federal University of Santa Catarina, Rua Pedro João Pereira, 150, CEP 88.905-120, Araranguá, SC, Brazil.

出版信息

Lasers Med Sci. 2022 Dec;37(9):3363-3377. doi: 10.1007/s10103-022-03648-3. Epub 2022 Oct 6.

DOI:10.1007/s10103-022-03648-3
PMID:36201144
Abstract

Tissue injuries that affect the skin and/or adjacent tissues and are usually over a bony prominence are called pressure injuries. The prevalence of these dysfunctions remains high, and despite technological advances, there is no consensus on the most appropriate treatment. The objective of this review was to evaluate the efficacy of photobiomodulation (PBM), ultrasound, and high-frequency electrophysical agents in the healing of pressure injuries in adults and the elderly. The search was conducted in the PubMed, Embase, Cochrane Library, Web of Science, and PEDro databases; in clinical trial records, a list of references of the selected articles, as well as through manual search (Google), of the last 5 years in humans in English and Portuguese. Nine thousand and sixty-seven studies were identified, 13 pre-selected, and 6 were included in this systematic review. PBM showed similar efficacy to other technologies indicated in other studies in healing pressure injuries. PBM with red wavelength (660 nm) in stages 2 and 3 pressure injuries effectively promoted healing compared to standard care. It was observed that the use of PBM accelerates tissue repair in pressure injuries; therapeutic ultrasound showed similar efficacy to other electrophysical agents but was effective in reducing the area of pressure injuries when comparing pre- and post-intervention. No clinical studies using the high-frequency electrophysical agent have been described in the last 5 years.

摘要

会导致皮肤和/或相邻组织损伤且通常发生在骨突出部位的损伤被称为压力性损伤。尽管技术不断进步,但这些功能障碍的患病率仍然很高,且对于最适宜的治疗方法尚未达成共识。本综述旨在评估光生物调节(PBM)、超声和高频物理因子在成人和老年人压力性损伤愈合中的疗效。检索了 PubMed、Embase、Cochrane Library、Web of Science 和 PEDro 数据库;在临床试验记录中,还检索了入选文章的参考文献列表,以及通过手动搜索(Google)在过去 5 年内发表的英文和葡萄牙文文献。共确定了 9067 项研究,预筛选出 13 项,系统评价纳入了 6 项。PBM 在愈合压力性损伤方面与其他研究中推荐的其他技术具有相似的疗效。PBM 红色波长(660nm)在 2 期和 3 期压力性损伤中有效促进愈合,优于标准护理。观察到 PBM 可加速压力性损伤组织修复;与其他物理因子相比,治疗性超声具有相似的疗效,但在比较干预前后时,可有效减小压力性损伤面积。在过去 5 年内,尚未有描述使用高频物理因子治疗压力性损伤的临床研究。

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本文引用的文献

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Clinical effects of high-intensity laser therapy on patients with chronic refractory wounds: a randomised controlled trial.高强度激光治疗慢性难治性伤口的临床效果:一项随机对照试验。
BMJ Open. 2021 Jul 12;11(7):e045866. doi: 10.1136/bmjopen-2020-045866.
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Comparison of photobiomodulation in the treatment of skin injury with an open wound in mice.比较光生物调节治疗小鼠开放性皮肤损伤的效果。
Lasers Med Sci. 2021 Dec;36(9):1845-1854. doi: 10.1007/s10103-020-03216-7. Epub 2021 Jan 25.
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Effect of Photobiomodulation on Repairing Pressure Ulcers in Adult and Elderly Patients: A Systematic Review.
光生物调节作用(100毫瓦)应用于纹身皮肤时的注意事项:一项横断面研究。
Arch Dermatol Res. 2025 Feb 14;317(1):403. doi: 10.1007/s00403-025-03935-3.
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Influence of photobiomodulation and radiofrequency on the healing of pressure lesions in mice.光生物调节和射频对小鼠压力性损伤愈合的影响。
Lasers Med Sci. 2024 Nov 15;39(1):280. doi: 10.1007/s10103-024-04226-5.
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Topical hADSCs-HA Gel Promotes Skin Regeneration and Angiogenesis in Pressure Ulcers by Paracrine Activating PPARβ/δ Pathway.局部注射富含脂肪间充质干细胞的透明质酸凝胶通过旁分泌激活过氧化物酶体增殖物激活受体β/δ通路促进压迫性溃疡的皮肤再生和血管生成。
Drug Des Devel Ther. 2024 Oct 26;18:4799-4824. doi: 10.2147/DDDT.S474628. eCollection 2024.
光生物调节对成人和老年压疮患者修复作用的系统评价。
Photochem Photobiol. 2020 Jan;96(1):191-199. doi: 10.1111/php.13162. Epub 2019 Nov 10.
4
Photobiomodulation Therapy for Wound Care: A Potent, Noninvasive, Photoceutical Approach.用于伤口护理的光生物调节疗法:一种强效、无创的光药疗法。
Adv Skin Wound Care. 2019 Apr;32(4):157-167. doi: 10.1097/01.ASW.0000553600.97572.d2.
5
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Braz J Med Biol Res. 2018 Oct 18;51(12):e7862. doi: 10.1590/1414-431X20187862.
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