Machado Renata Saltiel, Viana Suane, Sbruzzi Graciele
Posgraduate Program Ciências do Movimento Humano of Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
, Porto Alegre, RS, Brazil.
Lasers Med Sci. 2017 May;32(4):937-944. doi: 10.1007/s10103-017-2150-9. Epub 2017 Jan 23.
The aim of this study was to evaluate the effects of low-level laser therapy (LLT) in pressure ulcers (PU) in humans through a systematic review of randomized studies. The search includes the databases MEDLINE, PEDro, Cochrane CENTRAL, and Lilacs, as well a manual search until May, 2016. This included randomized clinical trials of LLT compared with other interventions, different types of LLT, LLT placebo, or control in the treatment of PU. The outcomes evaluated were the ulcer area, healing rate, and overall healing rate. The risk of bias was evaluated using the tool of the Cochrane Collaboration, and the results were analyzed descriptively. From the 386 articles identified, only four studies were included, with two LLT used with single wavelength (1: 904 nm vs. control and 2: 940 nm vs. 808 nm vs. 658 nm vs. placebo) and two LLT used to probe cluster. One study compared to different single wavelengths showed a significant 71% reduction of the PU and an improved healing rate in which 47% of PU healed completely after 1 month of therapy with the use of LLT with a wavelength of 658 nm compared with other lengths. The other analyzed wavelengths were not significant in the assessed outcomes. Significant results were observed in the use of LLT with a 658 nm wavelength, and no evidence was found for use of wavelengths above that for the treatment of PU. Therefore, we also found no evidence in the laser used to probe the cluster.Registration number: CRD42016036648.
本研究旨在通过对随机研究的系统评价，评估低强度激光疗法（LLT）对人类压疮（PU）的影响。检索范围包括MEDLINE、PEDro、Cochrane CENTRAL和Lilacs数据库，以及截至2016年5月的手工检索。这包括LLT与其他干预措施、不同类型的LLT、LLT安慰剂或对照在治疗PU方面的随机临床试验。评估的结果包括溃疡面积、愈合率和总体愈合率。使用Cochrane协作网的工具评估偏倚风险，并对结果进行描述性分析。从识别出的386篇文章中，仅纳入了四项研究，其中两项研究使用单一波长的LLT（1：904nm与对照组对比，以及2：940nm与808nm、658nm与安慰剂对比），另外两项研究使用LLT进行簇状探测。一项比较不同单一波长的研究显示，PU显著减少了71%，愈合率有所提高，其中使用波长为658nm的LLT治疗1个月后，47%的PU完全愈合，与其他波长相比效果更佳。其他分析的波长在评估结果中无显著差异。在使用658nm波长的LLT时观察到显著结果，未发现高于该波长用于治疗PU的证据。因此，我们在用于簇状探测的激光方面也未发现证据。注册号：CRD42016036648。
