Burel Julien, Cornacchini Jonathan, Garnier Matthieu, Patrier Sophie, Guigné Albane, Gerardin Emmanuel, Papagiannaki Chrysanthi, Sourour Nader, Shotar Eimad, Premat Kévin, Laporte Claire, Clarençon Frédéric
Department of Radiology, Rouen University Hospital, Rouen, France.
GRC BioFast, Sorbonne University, Paris, France.
Front Neurol. 2022 Sep 20;13:925763. doi: 10.3389/fneur.2022.925763. eCollection 2022.
Indications for mechanical thrombectomy in acute ischemic stroke are increasing, resulting in the continuous development of new devices and techniques. Therefore, there is a need for a realistic testing and training environment that offers the opportunity to practice different procedures and test the latest devices. Some authors have described the use of the human placenta as a model for neurointerventional surgery, with striking similarities to real-life conditions. This model has many advantages, including its relatively low cost and minimal infrastructure requirements, with fewer ethical concerns compared to animal models. So far, some preparation and set-up details were missing, and only arteries from the chorionic plate were used. This article provides the necessary clarifications and a mapping of the chorionic plate veins, so that the use of this model, which is particularly well suited for mechanical thrombectomy, can be as easy and wide as possible. A video explaining how to prepare the model is provided.
急性缺血性卒中机械取栓的适应证不断增加，促使新设备和技术持续发展。因此，需要一个逼真的测试和训练环境，以提供练习不同操作和测试最新设备的机会。一些作者描述了将人胎盘用作神经介入手术模型，它与实际情况有惊人的相似之处。该模型有许多优点，包括成本相对较低、基础设施要求 minimal，与动物模型相比，伦理问题较少。到目前为止，一些准备和设置细节尚不完善，且仅使用了来自绒毛板的动脉。本文提供了必要的说明以及绒毛板静脉的图谱，以便这种特别适合机械取栓的模型能够尽可能简便且广泛地应用。还提供了一个解释如何制备该模型的视频。
