Bidgood K A, Steer P J
Br J Obstet Gynaecol. 1987 Jun;94(6):518-22. doi: 10.1111/j.1471-0528.1987.tb03143.x.
Uterine activity was measured in 60 women whose first labour was progressing slowly in the active phase. The mean level of active contraction area (uterine activity integral, UAI) before oxytocin augmentation was 898 (SD 458) kPas/15 min. UAI increased significantly with time, even in women not given oxytocin. UAI increased logarithmically with increasing oxytocin infusion rate. Levels of uterine activity before and after oxytocin infusion are correlated positively such that the higher the initial level of UAI the higher the UAI in response to oxytocin. However, the regression line approaches the line of identity such that even with high doses of oxytocin UAI would not be likely to exceed 2500 kPas/15 min. There is a positive correlation between uterine activity and cervical dilatation rate in unstimulated labour; however, this is less evident following oxytocin infusion. Increases in uterine activity below 1200 kPas/15 min result from both higher frequency and active pressure, whereas above 1200 kPas/15 min any increase is due mainly to a rise in frequency.
对60名第一产程活跃期进展缓慢的女性进行了子宫活动测量。在使用缩宫素加强宫缩前，主动收缩面积（子宫活动积分，UAI）的平均水平为898（标准差458）kPa·s/15分钟。即使未使用缩宫素的女性，UAI也随时间显著增加。UAI随缩宫素输注速率的增加呈对数增加。缩宫素输注前后的子宫活动水平呈正相关，即UAI的初始水平越高，对缩宫素反应后的UAI越高。然而，回归线接近恒等线，因此即使使用高剂量缩宫素，UAI也不太可能超过2500 kPa·s/15分钟。在未使用缩宫素的产程中，子宫活动与宫颈扩张速率呈正相关；然而，在使用缩宫素后这种相关性不太明显。子宫活动低于1200 kPa·s/15分钟时的增加是由于频率和主动压力的增加，而高于1200 kPa·s/15分钟时，任何增加主要是由于频率的升高。
