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科技融合推动颅骨重建材料的范式转变

Paradigm Shift in Materials for Skull Reconstruction Facilitated by Science and Technological Integration.

作者信息

Beri Arushi, Pisulkar Sweta G, Bansod Akansha V, Dahihandekar Chinmayee

机构信息

Prosthodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Prosthodontics and Crown & Bridge, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2022 Sep 3;14(9):e28731. doi: 10.7759/cureus.28731. eCollection 2022 Sep.

DOI:10.7759/cureus.28731
PMID:36204019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9528855/
Abstract

The surgical repair of a bone deficiency in the skull caused by a prior procedure or accident is known as cranioplasty. There are various types of cranioplasties, but the majority entail raising the scalp and reshaping the skull using either the original piece of bone from the skull or a specially molded graft created from Titanium (plate or mesh), artificial bone in place of, a stable biomaterial (prefabricated customized implant to match the exact contour and shape of the skull). Cranioplasty, one of the oldest surgical treatments for cranial abnormalities, has undergone several changes throughout the years to discover the best material to improve patient outcomes. Various materials have been utilized in cranioplasty throughout history. As biomedical technology progresses, surgeons will have access to new materials. There is still no agreement on the optimum material, and research into biologic and nonbiologic alternatives is ongoing in the hopes of finding the finest reconstruction material. The materials and techniques used in cranioplasty are covered in this article.

摘要

因先前手术或事故导致颅骨缺损的外科修复称为颅骨成形术。颅骨成形术有多种类型,但大多数需要掀起头皮,并用取自颅骨的原骨片或由钛(板或网)制成的特制模制移植物、替代人工骨的稳定生物材料(预制定制植入物以匹配颅骨的确切轮廓和形状)重塑颅骨。颅骨成形术是治疗颅骨异常最古老的外科手术之一,多年来经历了几次变革,以探寻改善患者预后的最佳材料。历史上,颅骨成形术中使用过各种材料。随着生物医学技术的进步,外科医生将能够使用新材料。对于最佳材料仍未达成共识,对生物和非生物替代材料的研究仍在进行,以期找到最佳的重建材料。本文涵盖了颅骨成形术中使用的材料和技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c48/9528855/05141ae9e6a2/cureus-0014-00000028731-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c48/9528855/05141ae9e6a2/cureus-0014-00000028731-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c48/9528855/05141ae9e6a2/cureus-0014-00000028731-i01.jpg

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Cranioplasty with hydroxyapatite or acrylic is associated with a reduced risk of all-cause and infection-associated explantation.使用羟基磷灰石或丙烯酸进行颅骨修复术与降低全因和感染相关的假体取出风险相关。
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颅骨重建中的数字化:革新精度与创新
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In vivo validation of highly customized cranial Ti-6AL-4V ELI prostheses fabricated through incremental forming and superplastic forming: an ovine model study.通过增量成形和超塑成形制造的高度定制化颅 Ti-6AL-4VELI 假体的体内验证:绵羊模型研究。
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Explanted Skull Flaps after Decompressive Hemicraniectomy Demonstrate Relevant Bone Avitality-Is Their Reimplantation Worth the Risk?减压性颅骨切除术后取出的颅骨瓣显示出相关的骨无活力——将其重新植入值得冒风险吗?
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Composite grafts made of polycaprolactone fiber mats and oil-based calcium phosphate cement pastes for the reconstruction of cranial and maxillofacial defects.聚己内酯纤维垫和油基磷酸钙水泥糊复合材料移植物在颅颌面骨缺损重建中的应用。
Clin Oral Investig. 2023 Jun;27(6):3199-3209. doi: 10.1007/s00784-023-04932-4. Epub 2023 Mar 3.
使用游离组织移植和定制聚醚醚酮植入物对慢性感染的大型颅骨缺损进行分期重建。
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