Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology (HUST), Wuhan, People's Republic of China.
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, People's Republic of China.
BMC Health Serv Res. 2022 Oct 7;22(1):1238. doi: 10.1186/s12913-022-08580-4.
Pharmacy intravenous admixture service (PIVAS) center has emerged as an important department of hospital as it can improve occupational protection and ensure the safety and effectiveness of intravenous infusions. However, medication errors were considered to be a significant challenge in PIVAS, so information-intelligence technologies were introduced to optimize the management of PIVAS. Our article summarized the application of information-intelligence technologies in PIVAS of a large third-class A hospital in China, and provided an example for PIVAS in other hospitals at home and abroad.
Prescription-reviewing rules containing intravenous medications and infusion solution guideline were recorded in the database of prescription-cheking system. Drugs information were recorded in the PIVAS management system with special identification and warning labels to reduce intravenous infusion errors. Automatic labeling device was used to label the infusion bags, and the quality control program database of intelligent compounding robot for cytotoxic drugs was established ingeniously. Automatic sorting devices were applied for the third batch of finished infusion admixtures, and intelligent logistics robots were used to transport the infusion to the ward.
After establishing and implementing of prescription-reviewing rules in the prescription-cheking system database, the number of prescriptions checked by pharmacists increased from 18 to 43 per minute. The success rate of intervention with irrational medical orders increased from 85.89% to 99.06% (P < 0.05). By introducing various intelligent devices, automatic labeling significantly enhanced work efficiency and reduced the error rate (P < 0.001). Furthermore, the use of intelligent intravenous compounding robots significantly reduced the risk of errors (P < 0.001).
The application of information-intelligence technologies in PIVAS can improve work efficiency and reduce error risk. However, some intelligent devices have failed to achieve the expected effect in practical use, and further improvements are needed to meet the demands of PIVAS in the future.
药学静脉药物调配中心(PIVAS)作为医院的重要部门,能够提高职业防护水平,保障静脉输液的安全性和有效性。然而,用药错误被认为是 PIVAS 的重大挑战,因此引入了信息-智能技术来优化 PIVAS 的管理。本文总结了信息-智能技术在中国某大型三甲医院 PIVAS 的应用,并为国内外其他医院的 PIVAS 提供了范例。
将包含静脉用药的审方规则和输液指南录入审方系统数据库,在 PIVAS 管理系统中录入药品信息,并设置特殊标识和警示标签,减少静脉输液错误。使用自动贴签设备对输液袋进行贴签,巧妙地建立了细胞毒性药物智能调配机器人的质量控制程序数据库。对第三批成品输液混合液应用自动分拣设备,使用智能物流机器人将输液运送至病房。
在审方系统数据库中建立并实施审方规则后,药师审核处方的速度从 18 份/分钟提高到 43 份/分钟(P<0.05)。不合理医嘱干预成功率从 85.89%提高到 99.06%(P<0.05)。引入各种智能设备后,自动贴签显著提高了工作效率,降低了错误率(P<0.001)。此外,智能静脉药物调配机器人的使用显著降低了错误风险(P<0.001)。
信息-智能技术在 PIVAS 的应用可以提高工作效率,降低错误风险。然而,一些智能设备在实际应用中未能达到预期效果,需要进一步改进,以满足未来 PIVAS 的需求。