Institute of Cardiovascular Sciences, University of Birmingham, Medical School, Birmingham, UK.
University Hospitals Birmingham NHS Foundation Trust and Health Data Research UK Midlands, Birmingham, UK.
Eur Heart J. 2022 Oct 7;43(37):3578-3588. doi: 10.1093/eurheartj/ehac426.
Big data is central to new developments in global clinical science aiming to improve the lives of patients. Technological advances have led to the routine use of structured electronic healthcare records with the potential to address key gaps in clinical evidence. The covid-19 pandemic has demonstrated the potential of big data and related analytics, but also important pitfalls. Verification, validation, and data privacy, as well as the social mandate to undertake research are key challenges. The European Society of Cardiology and the BigData@Heart consortium have brought together a range of international stakeholders, including patient representatives, clinicians, scientists, regulators, journal editors and industry. We propose the CODE-EHR Minimum Standards Framework as a means to improve the design of studies, enhance transparency and develop a roadmap towards more robust and effective utilisation of healthcare data for research purposes.
大数据是全球临床科学新发展的核心，旨在改善患者的生活。技术进步导致了结构化电子医疗记录的常规使用，这有可能解决临床证据的关键空白。Covid-19 大流行展示了大数据和相关分析的潜力，但也暴露出了重要的缺陷。验证、验证和数据隐私，以及进行研究的社会任务，都是关键的挑战。欧洲心脏病学会和 BigData@Heart 联盟汇集了一系列国际利益相关者，包括患者代表、临床医生、科学家、监管机构、期刊编辑和行业。我们提出了 CODE-EHR 最低标准框架，作为一种改进研究设计、提高透明度和制定更强大、更有效的医疗保健数据研究利用路线图的手段。
