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金属植入物固定髌骨骨折的并发症和再次手术风险明显高于非金属植入物:系统评价和荟萃分析。

Fixation of patella fractures with metallic implants is associated with a significantly higher risk of complications and re-operations than non-metallic implants: a systematic review and meta-analysis.

机构信息

Orthopaedic and Trauma Surgery Unit, AOU Sant'Andrea, La Sapienza University of Rome, Via di Grottarossa, 1035-1038, 00189, Rome, Italy.

Department of Orthopaedic Surgery, University of Rome "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy.

出版信息

Int Orthop. 2022 Dec;46(12):2927-2937. doi: 10.1007/s00264-022-05565-0. Epub 2022 Oct 8.

Abstract

PURPOSE

The use of metallic implants for the treatment of patella fractures often involves complications related to the hardware. As a result, there has been a considerable focus on the use of non-metallic implants. The aim of this study was to determine the differences in clinical outcomes, including the rates of complications and re-operations following the surgical management of patellar fractures with metallic versus non-metallic implants.

METHODS

The systematic review was conducted in accordance with PRISMA guidelines. Two investigators independently applied the search strategy to PubMed, SCOPUS, Google Scholar, and Cochrane databases, limited to publications between 1st January 2000 to 30st September 2021. The search strategy identified studies in which there was a comparison between the clinical outcome of the metallic and non-metallic fixation. Meta-analysis was conducted according to the Cochrane Collaboration and Quality of Reporting of Meta-Analysis (QUORUM) guidelines.

RESULTS

A total of 19 studies were selected for the systematic review and seven studies for the meta-analysis. Two hundred ninety-sixt patients formed the pooled study population for the meta-analysis. The outcomes evaluated in the meta-analysis were range of motion (ROM), complications, and re-operation rates. There was no significant difference between groups regarding ROM, but the risk ratio (RR) of re-operation (RR 0.19, 95% CI [0.09-0.41]) and complications (RR 0.30, 95% CI [0.17-0.55]) was significantly in favor of fixation with non-metallic implants.

CONCLUSION

The use of non-metallic implants for fixation of patella fractures was associated with significantly lower risk of complications and re-operations than fixation with metallic implants, without any difference between groups with respect to the final range of motion or functional outcome measures.

摘要

目的

在治疗髌骨骨折时使用金属植入物常涉及与硬件相关的并发症。因此,人们对使用非金属植入物产生了浓厚的兴趣。本研究旨在确定使用金属与非金属植入物治疗髌骨骨折的临床结果差异,包括并发症发生率和手术后再手术率。

方法

本系统评价按照 PRISMA 指南进行。两名调查员独立应用搜索策略,检索了 PubMed、SCOPUS、Google Scholar 和 Cochrane 数据库,检索时间限定为 2000 年 1 月 1 日至 2021 年 9 月 30 日。该搜索策略确定了比较金属和非金属固定临床结果的研究。根据 Cochrane 协作和 Meta 分析报告质量(QUORUM)指南进行 Meta 分析。

结果

共筛选出 19 项系统评价研究和 7 项 Meta 分析研究。7 项 Meta 分析研究共纳入 296 名患者。Meta 分析评估的结果包括活动范围(ROM)、并发症和再手术率。两组之间 ROM 无显著差异,但非金属植入物固定的再手术风险比(RR)(RR 0.19,95%CI [0.09-0.41])和并发症风险比(RR)(RR 0.30,95%CI [0.17-0.55])明显更优。

结论

与金属植入物固定相比,使用非金属植入物固定髌骨骨折的并发症和再手术风险显著降低,而两组在最终 ROM 或功能结果测量方面无差异。

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