睡眠期间的脑循环及其与脑外血流动力学的关系。

Brain circulation during sleep and its relation to extracerebral hemodynamics.

作者信息

Lenzi P, Cianci T, Guidalotti P L, Leonardi G S, Franzini C

出版信息

Brain Res. 1987 Jul 7;415(1):14-20. doi: 10.1016/0006-8993(87)90264-2.

PMID:3620941

Abstract

Regional cerebral blood flow (rCBF) was measured in rabbits during the sleep-waking cycle, using radioactive microspheres. rCBF does not change significantly in the transition from wakefulness (W) to synchronized sleep (SS), while it significantly increases during desynchronized sleep (DS). No correlation was found between CBF changes and changes in cardiac output or regional blood flows in the transition from SS to DS. This suggests that the CBF increase in DS is not relevantly affected by changes in extracerebral hemodynamic factors.

摘要

使用放射性微球在兔的睡眠-觉醒周期中测量局部脑血流量（rCBF）。从觉醒（W）到同步睡眠（SS）的转变过程中，rCBF没有显著变化，而在去同步睡眠（DS）期间它显著增加。在从SS到DS的转变过程中，未发现CBF变化与心输出量或局部血流变化之间存在相关性。这表明DS期间CBF的增加与脑外血流动力学因素的变化没有显著关联。