大鼠睡眠-觉醒周期中脊髓血流的变化。

Spinal cord blood flow changes during the sleep-wake cycle in rat.

作者信息

Zoccoli G, Bach V, Nardo B, Cianci T, Lenzi P, Franzini C

机构信息

Institute of Human Physiology, University of Bologna, Italy.

出版信息

Neurosci Lett. 1993 Dec 12;163(2):173-6. doi: 10.1016/0304-3940(93)90375-u.

DOI:10.1016/0304-3940(93)90375-u

PMID:8309626

Abstract

Regional spinal cord blood flow was measured in rats during the sleep-wake cycle with the use of radioactive microspheres. Spinal cord blood flow decreases from wakefulness to quiet (synchronized) sleep while increasing in active (desynchronized) sleep. Blood-flow changes depend on changes in vascular resistance whose mechanisms have yet to be elucidated. Blood-gas tension or mean arterial pressure, however, do not play a relevant causal role.

摘要

利用放射性微球测量大鼠在睡眠-觉醒周期中的脊髓局部血流量。脊髓血流量从清醒状态到安静（同步）睡眠时减少，而在活跃（去同步）睡眠时增加。血流量变化取决于血管阻力的变化，其机制尚待阐明。然而，血气张力或平均动脉压并不起相关的因果作用。