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开放性骨盆骨折合并泌尿生殖系统损伤的综述。

A review of open pelvic fractures with concurrent genitourinary injuries.

机构信息

Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Health Sciences University, 450 Clarkson Avenue, MSC 30, Brooklyn, NY, 11203, USA.

Department of Orthopedic Surgery, New York University Langone Hospital, 150 55th Street, Brooklyn, NY, 11220, USA.

出版信息

Eur J Orthop Surg Traumatol. 2023 Jul;33(5):1515-1521. doi: 10.1007/s00590-022-03388-8. Epub 2022 Oct 9.

Abstract

INTRODUCTION

Open pelvic fractures (OPFs) are uncommon but potentially lethal traumatic injuries. Often caused by high energy blunt trauma, they can cause severe injury to abdominal and pelvic structures. We sought to conduct a review of the literature in order to ascertain the rates of genitourinary injury and vaginal laceration after OPF and the rates of resulting infection and mortality.

METHODS

A review of PubMed was conducted to identify studies reporting the rates of genitourinary injury from OPF. Study characteristics, patient characteristics, and outcomes were collected. The data were pooled, and descriptive statistics were obtained.

RESULTS

Eight studies encompassing 343 patients were included. Average age was 35.1 years (10-85.9), 28% were female, and the average Injury Severity Score was 26.5 (4-75). 95.5% of patients had a blunt mechanism of injury. Motor vehicle collision (23.9%), motorcycle accident (19.7%), and pedestrian struck (19.3%) were the most common etiologies. Overall mortality and infection rates were 31.2% and 18.7%, respectively. 19.7% of patients suffered an injury to the genitourinary system, and 32.4% of females sustained a vaginal laceration.

DISCUSSION

OPFs have the potential for extremely high morbidity and mortality. While much research has been done to prevent early mortality from hemorrhage, there is comparatively little research into late mortality stemming from infection and sepsis. Intravenous antibiotics are the mainstay of treatment, and local antibiotics usage has been encouraged. In patients with a vaginal laceration, it is important to provide antibiotic coverage for vaginal flora.

摘要

引言

开放性骨盆骨折(OPF)较为少见,但可能导致致命的创伤。它们通常由高能钝性创伤引起,可导致腹部和骨盆结构严重损伤。我们旨在对文献进行综述,以确定 OPF 后泌尿生殖系统损伤和阴道撕裂的发生率,以及由此导致的感染和死亡率。

方法

我们对 PubMed 进行了回顾,以确定报告 OPF 泌尿生殖系统损伤发生率的研究。收集了研究特征、患者特征和结局。对数据进行了汇总,并获得了描述性统计数据。

结果

纳入了 8 项共 343 例患者的研究。平均年龄为 35.1 岁(10-85.9),28%为女性,损伤严重程度评分平均为 26.5(4-75)。95.5%的患者有钝性损伤机制。机动车碰撞(23.9%)、摩托车事故(19.7%)和行人被撞(19.3%)是最常见的病因。总死亡率和感染率分别为 31.2%和 18.7%。19.7%的患者泌尿生殖系统受伤,32.4%的女性发生阴道撕裂。

讨论

OPF 有极高的发病率和死亡率。虽然有大量研究致力于预防出血引起的早期死亡,但对于感染和脓毒症引起的晚期死亡的研究相对较少。静脉内抗生素是治疗的主要方法,局部抗生素的使用也得到了鼓励。对于有阴道撕裂的患者,重要的是提供针对阴道菌群的抗生素覆盖。

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