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The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies.宿主与 SARS-CoV-2 的较量:固有免疫与病毒逃逸策略。
Mol Ther. 2022 May 4;30(5):1869-1884. doi: 10.1016/j.ymthe.2022.02.014. Epub 2022 Feb 14.
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叙利亚人群中与新冠病毒感染、相关行为、抗生素使用及耐药性有关的知识、态度和实践:一项横断面研究。

Knowledge, attitudes, and practices related to COVID-19 infection, related behavior, antibiotics usage, and resistance among Syrian population: A cross-sectional study.

作者信息

Swed Sarya, Shoib Sheikh, Almoshantaf Mohammad B, Hasan Walaa, Dean Yomna E, Tanas Yousef, Bohsas Haidara, Alibrahim Hidar, Hasan Mohammad M, Ezzdean Weaam, Ghaith Hazem S, Khairy Lina T, Bakkour Agyad, Hadi Hussein Muwaili Ali, Abdelmajid Fatima A A, Albuni Mhd K, Battikh Elias, Hadi Hussein Muwaili Dhuha, Qattea Rima, Motawea Karam R, Sawaf Bisher, Kamal Hamdy Elkalagi Nashaat, Ahmed Safaa M A, Aiash Hani

机构信息

Faculty of Medicine Aleppo University Aleppo Syria.

Department of Psychiatry Jawahar Lal Nerhu Memorial Hospital (JLNMH) Srinagar India.

出版信息

Health Sci Rep. 2022 Oct 3;5(6):e833. doi: 10.1002/hsr2.833. eCollection 2022 Nov.

DOI:10.1002/hsr2.833
PMID:36210879
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9528956/
Abstract

BACKGROUND AND AIMS

Antibiotic resistance is seen as a worldwide health risk as a result of the overuse of antibiotics. Many countries noted that antibiotic usage was high during the COVID-19 pandemic. The purpose of this study is to evaluate Syrians' knowledge, attitudes, and practice about the use of antibiotics and antibiotic resistance during the COVID-19 epidemic.

METHODS

A cross-sectional study was conducted using an online questionnaire to collect the data from the Syrian population from February 5 to March 4, 2022. Syrians 18 years or older all over the world were able to participate in this study. A convenience snowball sampling method was used. SPSS version 20.0 was used to analyze the data. To examine the results, binominal logistic regression was used. Statistical significance was defined as a  < 0.05.

RESULTS

Out of 2406 respondents, 60.2% knew that transmission of COVID-19 could occur even if the patient has not developed any symptoms, and 91.6% were able to recognize the main clinical symptoms of COVID-19. There was a statistically significant difference between male and female knowledge of COVID-19 ( = 0.002), with males having 3.78 ± 2.1 (2.7-3.87) and females scoring 3.93 ± 2.3 (3.7-4.1). Newly graduated students have more knowledge of COVID-19 than other subtypes of Job ( = 0.0001), and those with medical practice are more knowledgeable than those without ( = 0.0001). Only 16.6% answered that taking antibiotics would not speed up the recovery from all the infections. 65.3% answered correctly that misuse of antibiotics could cause antibiotic resistance.

CONCLUSION

Our study concluded that the Syrian population demonstrated good knowledge of COVID-19 and moderate acceptance of the new norm. Knowledge regarding antibiotic use and resistance and practice of preventive measures was poor, which can encourage the health authorities to develop community education programs to increase public awareness of the usage of antibiotics and safety protocols during the COVID-19 pandemic.

摘要

背景与目的

由于抗生素的过度使用,抗生素耐药性被视为一种全球健康风险。许多国家指出,在新冠疫情期间抗生素使用量很高。本研究的目的是评估叙利亚人在新冠疫情期间对抗生素使用及抗生素耐药性的知识、态度和行为。

方法

于2022年2月5日至3月4日采用在线问卷进行横断面研究,以收集叙利亚人群的数据。世界各地18岁及以上的叙利亚人都能够参与本研究。采用便利滚雪球抽样方法。使用SPSS 20.0版本分析数据。为检验结果,采用二项逻辑回归。统计学显著性定义为P < 0.05。

结果

在2406名受访者中,60.2%知道即使患者没有出现任何症状,新冠病毒也可能传播,91.6%能够识别新冠病毒的主要临床症状。男性和女性对新冠病毒的了解存在统计学显著差异(P = 0.002),男性得分3.78 ± 2.1(2.7 - 3.87),女性得分3.93 ± 2.3(3.7 - 4.1)。刚毕业的学生比其他职业类型的人对新冠病毒了解更多(P = 0.0001),有医疗工作经历的人比没有的人知识更丰富(P = 0.0001)。只有16.6%的人回答服用抗生素不会加速所有感染的康复。65.3%的人正确回答滥用抗生素会导致抗生素耐药性。

结论

我们的研究得出结论,叙利亚人群对新冠病毒表现出良好的了解,对新规范有适度的接受度。关于抗生素使用和耐药性以及预防措施的实践方面的知识较差,这可促使卫生当局制定社区教育项目,以提高公众在新冠疫情期间对抗生素使用和安全规程的认识。