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伊朗成年人中的肾结石:一项基于队列的横断面研究中的患病率及社会经济不平等评估

Kidney stones among Iranian adults: Prevalence and socioeconomic inequality assessment in a cohort-based cross-sectional study.

作者信息

Zahirian Moghadam Telma, Pourfarzi Farhad, Mohseni Rad Hamed, Zandian Hamed

机构信息

Social Determinants of Health Research Center Ardabil University of Medical Sciences Ardabil Iran.

Digestive Disease Research Center Ardabil University of Medical Sciences Ardabil Iran.

出版信息

Health Sci Rep. 2022 Oct 3;5(6):e877. doi: 10.1002/hsr2.877. eCollection 2022 Nov.

Abstract

BACKGROUND AND AIMS

Kidney stone disease is a crystal concretion formed usually within the kidneys. The worldwide prevalence of kidney stones could be affected by numerous differences in socioeconomic, and environmental factors. The purpose of this study is to investigate kidney stones among Iranian adults aged between 35 and 70 years and the prevalence and evaluation of socioeconomic inequalities.

METHODS

In this, a cohort-based cross-sectional study was carried out among 20,427 participants of ArNCDs aged 35 and 70 years old. Kidney stone was defined as a dependent (and binary) variable while demographic and socioeconomic factors were considered independent variables. Multivariable logistic regression was used to identify the key socioeconomic factors affecting kidney stone prevalence in Ardabil.

RESULTS

The overall prevalence of kidney stones was 17.6 (95% confidence interval [CI]: 16.1-19.2) out of which 21.53% and 14.36% pertained to men and women and 14.18% and 23.17% pertained to the poorest and richest groups, respectively. There was a significant difference in the prevalence of kidney stones between men and women in terms of age, marital status, education level, chronic disease, body mass index, and socioeconomic status (<0.001). The prevalence of kidney stones had a positive correlation with age (1.7, 95% [CI]: 1.42-2.04) and socioeconomic status (1.5, 95% [CI]: 1.34-1.69), where the odds of kidney stones increased significantly by increasing age and socioeconomic status. Moreover, the kidney stone concentration index showed a pro-rich distribution wherein it was more common among wealthy people (higher socioeconomic status) 0.062 (95% [CI]: 0.051-0.072).

CONCLUSION

The results of this study showed that there is significant inequality in the prevalence of kidney stones, where it was more common among the richest people. In addition, being men and old age are significantly related to kidney stones, so policymakers and physicians should consider these factors.

摘要

背景与目的

肾结石病是一种通常在肾脏内形成的晶体结石。全球肾结石患病率可能受到社会经济和环境因素诸多差异的影响。本研究的目的是调查年龄在35至70岁之间的伊朗成年人中的肾结石情况以及社会经济不平等的患病率和评估。

方法

在此,对20427名年龄在35至70岁之间的非传染性疾病队列参与者进行了基于队列的横断面研究。肾结石被定义为因变量(二元变量),而人口统计学和社会经济因素被视为自变量。多变量逻辑回归用于确定影响阿尔达比勒肾结石患病率的关键社会经济因素。

结果

肾结石的总体患病率为17.6(95%置信区间[CI]:16.1 - 19.2),其中男性患病率为21.53%,女性患病率为14.36%,最贫困和最富有群体的患病率分别为分别为14.18%和23.17%。在年龄、婚姻状况、教育水平、慢性病、体重指数和社会经济地位方面,男性和女性的肾结石患病率存在显著差异(<0.001)。肾结石患病率与年龄(1.7,95%[CI]:1.42 - 2.04)和社会经济地位(1.5,95%[CI]:1.34 - 1.69)呈正相关,其中肾结石的患病几率随着年龄和社会经济地位的增加而显著增加。此外,肾结石浓度指数显示出有利于富人的分布,即在富人(较高社会经济地位)中更为常见,为0.062(95%[CI]:0.051 - 0.072)。

结论

本研究结果表明,肾结石患病率存在显著不平等,在最富有的人中更为常见。此外,男性和老年与肾结石显著相关,因此政策制定者和医生应考虑这些因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a74/9528948/627dc3e7708c/HSR2-5-e877-g001.jpg

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