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白内障超声乳化联合卡胡克双刃小梁切除术的六个月随访

Six months' follow-up of combined phacoemulsification-kahook dual blade excisional goniotomy.

作者信息

Mechleb Nicole, Tomey Karim, Cherfan Daniel, Nemr Antony, Cherfan Georges, Dorairaj Syril, Khoueir Ziad

机构信息

Faculty of Medicine, Saint-Joseph University, Byblos, Lebanon.

Department of Glaucoma, Beirut Eye and ENT Specialist Hospital, Byblos, Lebanon.

出版信息

Saudi J Ophthalmol. 2022 Aug 29;36(2):195-200. doi: 10.4103/sjopt.sjopt_151_21. eCollection 2022 Apr-Jun.

Abstract

PURPOSE

This study reports on the combination of excisional goniotomy and cataract extraction in the management of glaucoma in terms of intraocular pressure (IOP) and glaucoma medication reduction.

METHODS

This is a retrospective case series. Twenty-eight eyes of 22 patients with the diagnosis of cataract and ocular hypertension or glaucoma of any stage underwent combined phacoemulsification and Kahook Dual Blade (KDB) goniotomy, between March 2019 and September 2020. The parameters evaluated were postoperative best-corrected visual acuity, mean IOP reduction, number of IOP-lowering medications, and the surgical success rate defined as IOP reduction >20% and/or reduction in glaucoma medications >1.

RESULTS

The mean IOP reduction at 6 months was 4.5 mmHg ( = 0.0007), which translates to 24.9% reduction from preoperative IOP. The mean preoperative number of glaucoma medications was 2.9 ± 1.0 (median of 3). It was reduced to 1.1 ± 1.1 (median of 1.5), 1.46 ± 1.17 (median of 2), 1.44 ± 1.28 (median of 2), and 1.56 ± 1.28 (median of 2) at 1 week, 1 month, 3 months, and 6 months, respectively. Twenty-nine percent (8/28) of the patients were off glaucoma medications at 6 months and 46% (13/28) had a reduction of more than 50% of their glaucoma medications.

CONCLUSION

Combined phacoemulsification-KDB excisional goniotomy may be an effective and safe alternative to more invasive filtering surgery in glaucoma patients of any stage.

摘要

目的

本研究报告了在青光眼治疗中,切除性前房角切开术与白内障摘除术联合应用在降低眼压(IOP)和减少青光眼药物使用方面的情况。

方法

这是一项回顾性病例系列研究。2019年3月至2020年9月期间,22例诊断为白内障合并任何阶段高眼压症或青光眼的患者的28只眼睛接受了白内障超声乳化吸除术联合Kahook双刃刀(KDB)前房角切开术。评估的参数包括术后最佳矫正视力、平均眼压降低幅度、降低眼压药物的数量,以及定义为眼压降低>20%和/或青光眼药物减少>1种的手术成功率。

结果

6个月时平均眼压降低4.5 mmHg(=0.0007),相对于术前眼压降低了24.9%。术前青光眼药物的平均数量为2.9±1.0(中位数为3)。在1周、1个月、3个月和6个月时分别降至1.1±1.1(中位数为1.5)、1.46±1.17(中位数为2)、1.44±1.28(中位数为2)和1.56±1.28(中位数为2)。29%(8/28)的患者在6个月时停用了青光眼药物,46%(13/28)的患者青光眼药物减少了50%以上。

结论

白内障超声乳化吸除术联合KDB切除性前房角切开术可能是各阶段青光眼患者替代更具侵入性的滤过性手术的一种有效且安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc80/9535917/972e5f646c71/SJO-36-195-g002.jpg

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