Ogunkoya John Omotola, Ogunmola Marion Itohan, Ogunlade Akinwale Folarin, Ladele Akindele Emmanuel
Benjamin Carson Snr. College of Health and Medical Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria.
Division of Respiratory Medicine and Allergy, Department of Medicine, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.
Case Rep Pulmonol. 2022 Sep 29;2022:9596285. doi: 10.1155/2022/9596285. eCollection 2022.
Acute pulmonary embolism (APE) is a common cause of morbidity and mortality all over the world. Sudden onset dyspnea and chest pain are characteristic. Prior to our index case, only two previous cases of bilateral pulmonary thromboembolism were reported in black Africans and the first to be associated with COVID-19 vaccination. These cases were seen and described in middle-aged men. . A 59-year-old man presented with a 2 week history of sudden onset dyspnea and a week history of productive cough. No associated chest pain or hemoptysis. No preceding history suggestive of leg pain/swelling. The patient had the booster dose of moderna (mRNA) COVID-19 vaccine a month before the onset of symptoms. There was associated anorexia, generalized body pain, joint pain, and weakness. He had reduced oxygen saturation at presentation with tachycardia. CTPA showed nearly occlusive right and left pulmonary arteries.
Bilateral acute pulmonary embolism is rare all over the world. Its association with COVID-19 vaccine administration is even rarer. However, the clinical presentations and investigation findings are similar to the descriptions available in the literature for unilateral APE.
急性肺栓塞（APE）是全球发病和死亡的常见原因。突发呼吸困难和胸痛是其特征。在我们的索引病例之前，仅有两例双侧肺血栓栓塞病例在非洲黑人中被报道，且首例与新冠病毒疫苗接种相关。这些病例见于中年男性。一名59岁男性，有2周突发呼吸困难病史和1周咳痰病史。无相关胸痛或咯血。无提示腿部疼痛/肿胀的既往史。患者在症状出现前一个月接种了莫德纳（mRNA）新冠病毒疫苗加强针。伴有厌食、全身疼痛、关节疼痛和虚弱。就诊时氧饱和度降低且心动过速。CTPA显示左右肺动脉几乎闭塞。
双侧急性肺栓塞在全球都很罕见。其与新冠病毒疫苗接种的关联更为罕见。然而，临床表现和检查结果与文献中关于单侧APE的描述相似。
