Tiwari Richa, Kumari Anju
Department of Anaesthesia and Intensive Care, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Indian J Crit Care Med. 2022 Sep;26(9):1049-1051. doi: 10.5005/jp-journals-10071-24311.
Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and spreads out "like a brush Fire" into the surrounding basis pontis. Extrapontine sites such as internal capsule, basal ganglia, cerebellum, and cerebrum can also be affected. We report a case of 60-year-old male with history of chronic alcoholism who presented to us with severe neurological deficits 10 days after his episode of severe hyponatremia.
Tiwari R, Kumari A. Central Pontine Myelinolysis: A Case Report. Indian J Crit Care Med 2022;26(9):1049-1051.
经典的中央桥脑髓鞘溶解症（CPM）是由于血清渗透压迅速升高所致。大多数病例与慢性酒精滥用、营养不良、利尿剂滥用及低钠血症病史有关。CPM的病理过程始于中缝附近的脑桥中部，并“如燎原之火”般蔓延至周围的脑桥基底部。脑桥外部位如内囊、基底节、小脑和大脑也可受累。我们报告一例60岁有慢性酒精中毒病史的男性，在严重低钠血症发作10天后出现严重神经功能缺损。
蒂瓦里R，库马里A。中央桥脑髓鞘溶解症：一例报告。《印度重症监护医学杂志》2022；26（9）：1049 - 1051。
