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可生物降解材料在脑血管支架中潜在应用的现状与展望。

Current status and outlook of potential applications of biodegradable materials in cerebral vascular stents.

机构信息

Dalian Medical University, Graduate School, 9 West section of Lushun South Road, Dalian, 116044, China.

General Hospital of Northern Theater Command, Institute of Neuroscience, Shenyang, Liaoning, China.

出版信息

Neurosurg Rev. 2022 Dec;45(6):3565-3571. doi: 10.1007/s10143-022-01876-3. Epub 2022 Oct 10.

DOI:10.1007/s10143-022-01876-3
PMID:36214907
Abstract

The treatment of intracranial aneurysms (IAs) has undergone a very significant transformation in recent decades, and endovascular interventions have gradually become one of the most common treatments. As permanent metal stents can cause some degree of long-term damage to patients, biodegradable stent materials are emerging as attractive potential alternatives. By reviewing the current research status and the advantages and disadvantages of existing biodegradable biomaterials, this review expects to provide a valuable reference for subsequent research on biodegradable biomaterials.

摘要

颅内动脉瘤(IAs)的治疗在最近几十年发生了重大转变,血管内介入治疗已逐渐成为最常用的治疗方法之一。由于永久性金属支架可能会对患者造成一定程度的长期损害,因此可生物降解的支架材料作为一种有吸引力的潜在替代品正在出现。通过回顾当前的研究现状和现有可生物降解生物材料的优缺点,本文希望为后续可生物降解生物材料的研究提供有价值的参考。

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本文引用的文献

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Lumen-oriented versus wall-oriented treatment strategies for intracranial aneurysms - A systematic review of suggested therapeutic concepts.颅内动脉瘤的管腔导向与壁导向治疗策略——对建议治疗概念的系统评价
J Cereb Blood Flow Metab. 2022 Sep;42(9):1568-1578. doi: 10.1177/0271678X211057498. Epub 2021 Nov 19.
2
Aneurysmal Subarachnoid Hemorrhage: Review of the Pathophysiology and Management Strategies.颅内动脉瘤性蛛网膜下腔出血:病理生理学与治疗策略综述。
Curr Neurol Neurosci Rep. 2021 Jul 26;21(9):50. doi: 10.1007/s11910-021-01136-9.
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Advances in coatings on magnesium alloys for cardiovascular stents - A review.
Bioact Mater. 2024 Aug 30;42:124-139. doi: 10.1016/j.bioactmat.2024.08.019. eCollection 2024 Dec.
心血管支架用镁合金涂层的研究进展——综述
Bioact Mater. 2021 May 23;6(12):4729-4757. doi: 10.1016/j.bioactmat.2021.04.044. eCollection 2021 Dec.
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Research status of biodegradable metals designed for oral and maxillofacial applications: A review.用于口腔颌面应用的可生物降解金属的研究现状:综述
Bioact Mater. 2021 Apr 27;6(11):4186-4208. doi: 10.1016/j.bioactmat.2021.01.011. eCollection 2021 Nov.
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Biodegradable materials for bone defect repair.可生物降解材料在骨缺损修复中的应用。
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Additively manufactured biodegradable porous metals.增材制造可生物降解多孔金属
Acta Biomater. 2020 Oct 1;115:29-50. doi: 10.1016/j.actbio.2020.08.018. Epub 2020 Aug 25.
7
In vitro degradation of pure magnesium-the synergetic influences of glucose and albumin.纯镁的体外降解——葡萄糖和白蛋白的协同影响
Bioact Mater. 2020 Mar 9;5(2):318-333. doi: 10.1016/j.bioactmat.2020.02.015. eCollection 2020 Jun.
8
Additive manufacturing of magnesium alloys.镁合金的增材制造。
Bioact Mater. 2020 Jan 11;5(1):44-54. doi: 10.1016/j.bioactmat.2019.12.004. eCollection 2020 Mar.
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Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery.可生物降解 Zn-Cu 支架的体内长期研究:在猪冠状动脉中的 2 年植入评估。
Acta Biomater. 2019 Oct 1;97:657-670. doi: 10.1016/j.actbio.2019.08.012. Epub 2019 Aug 8.
10
The interaction of zinc and the blood-brain barrier under physiological and ischemic conditions.在生理和缺血条件下锌与血脑屏障的相互作用。
Toxicol Appl Pharmacol. 2019 Feb 1;364:114-119. doi: 10.1016/j.taap.2018.12.018. Epub 2018 Dec 27.