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黏液瘤、斑点状色素沉着和内分泌功能亢进综合征

The complex of myxomas, spotty pigmentation and endocrine overactivity.

作者信息

Leedman P J, Cohen A K, Matz L R

出版信息

Clin Endocrinol (Oxf). 1986 Nov;25(5):527-34. doi: 10.1111/j.1365-2265.1986.tb03605.x.

DOI:10.1111/j.1365-2265.1986.tb03605.x
PMID:3621620
Abstract

We describe a 40-year-old male with acromegaly, multiple and recurrent cutaneous myxomas, spotty cutaneous pigmentation, a mammary myxoma, a large-cell calcifying Sertoli cell tumour of the testis, and an unusual calcifying pigmented neuroectodermal tumour. He presented a combination of clinical and histological features not previously documented within the complex of myxomas, spotty pigmentation and endocrine overactivity, and therefore the findings broaden the spectrum of the syndrome.

摘要

我们描述了一名40岁男性,患有肢端肥大症、多发性复发性皮肤黏液瘤、散在性皮肤色素沉着、乳腺黏液瘤、睾丸大细胞钙化性支持细胞瘤以及一种罕见的钙化性色素性神经外胚层肿瘤。他表现出的临床和组织学特征组合在黏液瘤、散在性色素沉着和内分泌功能亢进综合征中此前未曾有过记录,因此这些发现拓宽了该综合征的范围。

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1
The complex of myxomas, spotty pigmentation and endocrine overactivity.黏液瘤、斑点状色素沉着和内分泌功能亢进综合征
Clin Endocrinol (Oxf). 1986 Nov;25(5):527-34. doi: 10.1111/j.1365-2265.1986.tb03605.x.
2
[Familial cases of cutaneous myxomas and spotty pigmentation (Carney's complex)].[皮肤黏液瘤和斑点状色素沉着的家族性病例(卡尼综合征)]
Nihon Hifuka Gakkai Zasshi. 1990 Sep;100(10):1047-52.
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The Carney complex (myxomas, spotty pigmentation, endocrine overactivity, and schwannomas).卡尼综合征(黏液瘤、斑点状色素沉着、内分泌功能亢进及神经鞘瘤)。
Dermatol Clin. 1995 Jan;13(1):19-26.
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Bilateral testicular large-cell calcifying sertoli cell tumor and recurrent cardiac myxoma in a patient with Carney's complex.一名患有卡尼综合征的患者出现双侧睾丸大细胞钙化性支持细胞瘤和复发性心脏黏液瘤。
Pediatr Radiol. 1995 Nov;25 Suppl 1:S236-7.
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Mucocutaneous pigmented spots and oral myxomas: the oral manifestations of the complex of myxomas, spotty pigmentation, and endocrine overactivity.黏膜皮肤色素沉着斑与口腔黏液瘤:黏液瘤、斑点状色素沉着及内分泌功能亢进综合征的口腔表现。
Oral Surg Oral Med Oral Pathol. 1987 Feb;63(2):175-83. doi: 10.1016/0030-4220(87)90308-2.
6
The complex of myxomas, spotty pigmentation, and endocrine overactivity.黏液瘤、斑点状色素沉着和内分泌功能亢进综合征。
Medicine (Baltimore). 1985 Jul;64(4):270-83. doi: 10.1097/00005792-198507000-00007.
7
Cutaneous myxomas. A major component of the complex of myxomas, spotty pigmentation, and endocrine overactivity.皮肤黏液瘤。黏液瘤、散在色素沉着和内分泌功能亢进综合征的主要组成部分。
Arch Dermatol. 1986 Jul;122(7):790-8. doi: 10.1001/archderm.122.7.790.
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Carney complex: the complex of myxomas, spotty pigmentation, endocrine overactivity, and schwannomas.卡尼综合征:由黏液瘤、斑点状色素沉着、内分泌功能亢进和神经鞘瘤组成的综合征。
Semin Dermatol. 1995 Jun;14(2):90-8. doi: 10.1016/s1085-5629(05)80003-3.
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[Carney's complex (myxomas, pigmented spots and endocrine hyperactivity). Apropos of a partial form in monozygotic twins].[卡尼综合征(黏液瘤、色素沉着斑和内分泌功能亢进)。关于一对单卵双胞胎中的部分病例]
Ann Pathol. 1988;8(3):239-43.
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Carney complex: in a patient with multiple blue naevi and lentigines, suspect cardiac myxoma.卡尼综合征:对于患有多发性蓝色痣和雀斑样痣的患者,应怀疑患有心脏黏液瘤。
Australas J Dermatol. 1999 Aug;40(3):158-60. doi: 10.1046/j.1440-0960.1999.00349.x.

引用本文的文献

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Acromegaly in Carney complex.卡尼综合征相关的肢端肥大症。
Pituitary. 2019 Oct;22(5):456-466. doi: 10.1007/s11102-019-00974-8.
2
Outcomes of Patients with Newly Diagnosed Cardiac Myxoma: A Retrospective Multicentric Study.新发心脏黏液瘤患者的结局:一项回顾性多中心研究。
Biomed Res Int. 2018 Feb 6;2018:8320793. doi: 10.1155/2018/8320793. eCollection 2018.
3
Bilateral eyelid myxomas in Carney's complex.卡尼综合征中的双侧眼睑黏液瘤
Br J Ophthalmol. 1991 Apr;75(4):251-2. doi: 10.1136/bjo.75.4.251.
4
Autosomal dominant transmission of the NAME syndrome (nevi, atrial myxoma, mucinosis of the skin and endocrine overactivity).
Hum Genet. 1991 Jan;86(3):300-4. doi: 10.1007/BF00202415.