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英国利益冲突的财务调查及心房颤动筛查:一项横断面研究。

Investigation into financial conflicts of interest and screening for atrial fibrillation in the UK: a cross-sectional study.

作者信息

McCartney Margaret, McCutcheon Calum, Cooke Millie, MacDonald Ronald, Mekwi Lena, Noruddin Ummi Haji, O'Keeffe Mary

机构信息

School of Medicine, University of St Andrews, St Andrews, UK

Medical School, University of Glasgow, Glasgow, UK.

出版信息

BMJ Evid Based Med. 2023 Feb;28(1):15-20. doi: 10.1136/bmjebm-2022-112004. Epub 2022 Oct 10.

Abstract

OBJECTIVE

To understand the relationship between financial conflicts of interest and recommendations for atrial fibrillation (AF) screening in the UK, via examining (1) if the UK media recommend for or against screening for AF, and (2) the financial conflicts of interests of AF screening commentators.

DESIGN

Cross-sectional study.

SETTING/PARTICIPANTS: References in UK mainstream media, Twitter, the UK's National Health Service (NHS), patient information websites and major UK heart-related charities regarding screening for AF between1 January 2018 and 31 July 2021.

OUTCOME MEASURES

Proportion of references advocating for, against and presenting balanced/neutral views on screening. Proportion of references citing commentators with financial conflicts of interest.

RESULTS

217 media stories were identified, containing 284 comments about screening for AF. 185/217 (85.3%) of articles were in favour, 9 (4.1%) were against and 23 (10.6%) were balanced. Quotations within were located from 194 commentators; 44 were quoted more than once. 41/44 (93.2%) were in favour of screening. Of these 41, 37 (90.2%) had a direct or indirect financial conflict of interest, including that due to a work role. Two were balanced and one was negative. 2553 tweets using 3 hashtags promoting screening were analysed. 2119 (83%) of the most impactful tweets promoting AF screening were by industry or organisations with industry funding. Of 23 NHS organisations holding information about funding and promoting AF screening online, 22 (96%) had industry funding. 9 (90%) of the top 10 patient information websites promoting AF screening had industry funding. Four main UK patient charities in this sector promoting screening received industry funding.

CONCLUSIONS

The vast majority of UK media promotes screening for AF, in contrast to the position of the independent UK National Screening Committee, which recommends against screening. Most commentators, internal NHS organisations and UK charities promoting screening had a direct or indirect financial conflict of interest. Independent information was rare. The reasons for this are unknown. Readers should consider the potential for the impact of financial conflicts on recommendations to screen.

摘要

目的

通过考察(1)英国媒体对房颤(AF)筛查是支持还是反对,以及(2)房颤筛查评论员的财务利益冲突情况,了解英国财务利益冲突与房颤筛查建议之间的关系。

设计

横断面研究。

设置/参与者:2018年1月1日至2021年7月31日期间英国主流媒体、推特、英国国家医疗服务体系(NHS)、患者信息网站以及英国主要心脏相关慈善机构中关于房颤筛查的参考文献。

观察指标

对筛查持支持、反对及呈现平衡/中立观点的参考文献比例。引用有财务利益冲突的评论员的参考文献比例。

结果

共识别出217篇媒体报道,包含284条关于房颤筛查的评论。185/217(85.3%)的文章表示支持,9篇(4.1%)表示反对,23篇(10.6%)观点平衡。文中引用了194位评论员的言论;44位被多次引用。41/44(93.2%)支持筛查。在这41位中,37位(90.2%)存在直接或间接的财务利益冲突,包括因工作角色导致的冲突。2位观点平衡,1位持反对意见。分析了使用3个促进筛查的主题标签的2553条推文。2119条(83%)最具影响力的促进房颤筛查的推文来自行业或有行业资金支持的组织。在23个在网上持有关于房颤筛查资金和推广信息的NHS组织中,22个(96%)有行业资金支持。推广房颤筛查的前10大患者信息网站中有9个(90%)有行业资金支持。该领域4个主要的英国患者慈善机构推广筛查获得了行业资金。

结论

与英国独立国家筛查委员会建议不进行筛查的立场相反,绝大多数英国媒体支持房颤筛查。大多数推广筛查的评论员、NHS内部组织和英国慈善机构存在直接或间接的财务利益冲突。独立信息很少见。原因不明。读者应考虑财务冲突对筛查建议可能产生的影响。

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