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手术入路和人工耳蜗电极对人颞骨耳蜗结构完整性的影响。

The effect of the surgical approach and cochlear implant electrode on the structural integrity of the cochlea in human temporal bones.

机构信息

Department of Otorhinolaryngology and Head & Neck Surgery, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, P.O. Box 85500, 3508, Utrecht, GA, The Netherlands.

UMC Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

出版信息

Sci Rep. 2022 Oct 12;12(1):17068. doi: 10.1038/s41598-022-21399-7.

Abstract

Cochlear implants (CI) restore hearing of severely hearing-impaired patients. Although this auditory prosthesis is widely considered to be very successful, structural cochlear trauma during cochlear implantation is an important problem, reductions of which could help to improve hearing outcomes and to broaden selection criteria. The surgical approach in cochlear implantation, i.e. round window (RW) or cochleostomy (CO), and type of electrode-array, perimodiolar (PM) or lateral wall (LW), are variables that might influence the probability of severe trauma. We investigated the effect of these two variables on scalar translocation (STL), a specific type of severe trauma. Thirty-two fresh frozen human cadaveric ears were evenly distributed over four groups receiving either RW or CO approach, and either LW or PM array. Conventional radiological multiplanar reconstruction (MPR) was compared with a reconstruction method that uncoils the spiral shape of the cochlea (UCR). Histological analysis showed that RW with PM array had STL rate of 87% (7/8), CO approach with LW array 75% (6/8), RW approach with LW array 50% (4/8) and CO approach with PM array 29% (2/7). STL assessment using UCR showed a higher inter-observer and histological agreement (91 and 94% respectively), than that using MPR (69 and 74% respectively). In particular, LW array positions were difficult to assess with MPR. In conclusion, the interaction between surgical approach and type of array should be preoperatively considered in cochlear implant surgery. UCR technique is advised for radiological assessment of CI positions, and in general it might be useful for pathologies involving the inner ear or other complex shaped bony tubular structures.

摘要

人工耳蜗植入术(CI)为重度听力障碍患者恢复听力。虽然这种听觉假体被广泛认为非常成功,但耳蜗植入过程中的结构性耳蜗创伤是一个重要问题,减少这种创伤有助于改善听力效果并拓宽选择标准。耳蜗植入术的手术入路,即圆窗(RW)或耳蜗造口术(CO),以及电极阵列的类型,即围壁式(PM)或侧壁式(LW),是可能影响严重创伤概率的变量。我们研究了这两个变量对特定类型严重创伤——标量移位(STL)的影响。32 只新鲜冷冻的人体尸耳平均分为四组,分别接受 RW 或 CO 入路和 LW 或 PM 阵列。对常规放射影像学多平面重建(MPR)和一种能展开耳蜗螺旋形状的重建方法(UCR)进行了比较。组织学分析显示,RW 联合 PM 阵列的 STL 发生率为 87%(7/8),CO 联合 LW 阵列为 75%(6/8),RW 联合 LW 阵列为 50%(4/8),CO 联合 PM 阵列为 29%(2/7)。使用 UCR 进行 STL 评估的观察者间和组织学间一致性更高(分别为 91%和 94%),而使用 MPR 的一致性分别为 69%和 74%。特别是,LW 阵列的位置用 MPR 很难评估。总之,在进行耳蜗植入手术时,应考虑手术入路和阵列类型之间的相互作用。建议使用 UCR 技术进行 CI 位置的放射学评估,并且一般来说,对于涉及内耳或其他复杂形状骨管状结构的病变,该技术可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d1/9556579/a5dbf4c35eb7/41598_2022_21399_Fig1_HTML.jpg

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