Vasil'ev A Iu
Fiziol Zh SSSR Im I M Sechenova. 1987 Jun;73(6):790-7.
Influence of noradrenaline and serotonin induced a drop in postcapillary resistance, capillary hydrostatic pressure and the capillary filtration coefficient whereas precapillary regional vascular resistance and the pre- to postcapillary resistance ratio increased. Histamine increased integral, postcapillary resistance and capillary hydrostatic pressure. Acetylcholine decreased pre and postcapillary resistance as well as the integral vascular one, the capillary filtration coefficient increasing, at that. Possible mechanisms of the effects of the drugs under study are discussed.
去甲肾上腺素和5-羟色胺的作用导致毛细血管后阻力、毛细血管流体静压和毛细血管滤过系数下降,而毛细血管前局部血管阻力以及毛细血管前与后阻力比值增加。组胺增加总阻力、毛细血管后阻力和毛细血管流体静压。乙酰胆碱降低毛细血管前和后阻力以及总血管阻力,此时毛细血管滤过系数增加。文中讨论了所研究药物作用的可能机制。