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西非 ICEMR 伙伴关系引导政策改善疟疾预防和控制。

The West Africa ICEMR Partnerships for Guiding Policy to Improve the Malaria Prevention and Control.

机构信息

Malaria Research and Training Center, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

University Clinical Research Center, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

出版信息

Am J Trop Med Hyg. 2022 Oct 11;107(4_Suppl):84-89. doi: 10.4269/ajtmh.21-1330.

Abstract

The Mali National Malaria Control Program (NMCP) recently established a phased set of goals for eliminating malaria in Mali by 2030. Over the past decade, the scale-up of NMCP-led malaria control interventions has led to considerable progress, as evidenced by multiple malariometric indicators. The West Africa International Center of Excellence in Malaria Research (WA-ICEMR) is a multidisciplinary research program that works closely with the NMCP and its partners to address critical research needs for malaria control. This coordinated effort includes assessing the effectiveness of control interventions based on key malaria research topics, including immune status, parasite genetic diversity, insecticide and drug resistance, diagnostic accuracy, malaria vector populations and biting behaviors, and vectorial capacity. Several signature accomplishments of the WA-ICEMR include identifying changing malaria age demographic profiles, testing innovative approaches to improve control strategies, and providing regular reporting on drug and insecticide resistance status. The NMCP and WA-ICEMR partnership between the WA-ICEMR and the NMCP offers a comprehensive research platform that informs the design and implementation of malaria prevention and control research programs. These efforts build local expertise and capacity for the next generation of malaria researchers and guide local policy, which is crucial in sustaining efforts toward eliminating malaria in West Africa.

摘要

马里国家疟疾控制规划(NMCP)最近制定了到 2030 年在马里消除疟疾的分阶段目标。在过去的十年中,NMCP 领导的疟疾控制干预措施的扩大化取得了相当大的进展,这一点从多个疟疾计量指标中可以得到证明。西非国际疟疾研究卓越中心(WA-ICEMR)是一个多学科研究项目,与 NMCP 及其合作伙伴密切合作,解决疟疾控制的关键研究需求。这一协调努力包括根据关键疟疾研究主题评估控制干预措施的有效性,这些主题包括免疫状态、寄生虫遗传多样性、杀虫剂和药物抗性、诊断准确性、疟疾媒介种群和叮咬行为以及媒介能力。WA-ICEMR 的几个标志性成就是确定了疟疾年龄人口结构的变化、测试了改进控制策略的创新方法,并定期报告药物和杀虫剂抗性状况。NMCP 和 WA-ICEMR 的合作关系为疟疾预防和控制研究计划的设计和实施提供了一个全面的研究平台。这些努力为下一代疟疾研究人员建立了当地的专业知识和能力,并指导了当地政策,这对于在西非维持消除疟疾的努力至关重要。

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