Department of Dermatology, Venereology and Andrology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Department of Psychiatry, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Sci Rep. 2023 Oct 16;13(1):17541. doi: 10.1038/s41598-023-44757-5.
Psoriasis is a chronic inflammatory condition associated with genetic and immunological susceptibility. The objective of the study was to evaluate pruritus and sleep quality in correlation (r) to psoriasis severity and to detect their impact on quality of life. Two hundred (200) patients with psoriasis were included. Psoriasis severity was determined using the psoriasis area severity index (PASI), the quality of life (QoL) was assessed by the psoriasis disability index (PDI) questionnaire, and the sleep quality was evaluated by the Pittsburgh sleep quality index (PSQI). Finally, the severity of itching was evaluated using a 12-item pruritus severity scale (PSS). Poor sleep quality was found in 16.0% of patients in this study. Poor sleep was detected among 50.0% of cases with severe psoriasis. PASI scores correlated significantly with sleep quality, duration and sleep disturbances (p < 0.001). The global PSQI and PASI were also significantly correlated (p = 0.004). In conclusion patients complaining of psoriasis exacerbated by pruritus and sleep problems demonstrated lower quality of life in all domains. Sleep disturbances and depressive symptoms impairing quality of life should be taken into consideration when screening patients suffering from psoriasis.
银屑病是一种与遗传和免疫易感性相关的慢性炎症性疾病。本研究的目的是评估瘙痒和睡眠质量与银屑病严重程度的相关性,并检测它们对生活质量的影响。共纳入 200 例银屑病患者。采用银屑病面积和严重程度指数(PASI)评估银屑病严重程度,采用银屑病残疾指数(PDI)问卷评估生活质量,采用匹兹堡睡眠质量指数(PSQI)评估睡眠质量。最后,采用 12 项瘙痒严重程度量表(PSS)评估瘙痒严重程度。在这项研究中,16.0%的患者睡眠质量较差。50.0%的重度银屑病患者存在睡眠不佳。PASI 评分与睡眠质量、睡眠时间和睡眠障碍显著相关(p<0.001)。整体 PSQI 和 PASI 也显著相关(p=0.004)。总之,瘙痒和睡眠问题加重的银屑病患者在所有领域的生活质量都较低。在筛查银屑病患者时,应考虑到睡眠障碍和影响生活质量的抑郁症状。