Farmacia, Investigación Ramón y Cajal, Hospital Universitario Ramón & Cajal, 28034 Madrid, Spain.
Responsable Sistemas Información Farmacia, Subdirección General de Farmacia y Productos Sanitarios Comunidad Autónoma de Madrid, Paseo de la Castellana, 280, 28046 Madrid, Spain.
Nutrients. 2022 Sep 20;14(19):3892. doi: 10.3390/nu14193892.
We aimed to analyse the impact of COVID-19 during 2020 and 2021 on the prescription of enteral nutritional support and its expenditure in the Community of Madrid, Spain, compared to pre-pandemic data from 2016 in the general population vs. elderly. We analysed official electronic prescriptions of all public hospitals of the Community of Madrid. The population over 75 years of age have the higher prescription of nutritional supplements (p < 0.001 vs. other age groups), with no differences between the 45−64 age group compared to the 65−74 age group (χ2 = 3.259, p = 0.196). The first wave of COVID-19 or the first time there was a real awareness of the virus in Spain is similar in a way to the first peak of prescription of enteral nutrition in March 2020. The second peak of prescription was observed in the over 75 age group in July 2020, being more pronounced in December 2020 and March−April of the following year (F = 7.863, p = 0.041). The last peaks correspond to summer 2021 and autumn of the same year (p = 0.031—year 2021 vs. 2020, p = 0.011—year 2021 vs. 2019), where a relationship between increased prescription of enteral nutrition and COVID-19 cases is observed. High-protein and high-calorie dietary therapies were the most prescribed in patients with or without diabetes. All of this entailed higher cost for the Community of Madrid. In conclusion, COVID-19 significantly affected the prescription of nutritional support, especially in the population over 75 years of age.
我们旨在分析 2020 年和 2021 年 COVID-19 对西班牙马德里社区肠内营养支持处方及其支出的影响,并与 2016 年普通人群和老年人的大流行前数据进行比较。我们分析了马德里社区所有公立医院的官方电子处方。75 岁以上人群的营养补充剂处方量较高(p < 0.001 与其他年龄组相比),45-64 岁年龄组与 65-74 岁年龄组之间无差异(χ2 = 3.259,p = 0.196)。COVID-19 的第一波或西班牙首次真正意识到该病毒的时间与 2020 年 3 月肠内营养处方的第一个高峰相似。2020 年 7 月,75 岁以上人群观察到第二个处方高峰,在 2020 年 12 月和次年 3 月至 4 月更为明显(F = 7.863,p = 0.041)。最后几个高峰出现在 2021 年夏季和同年秋季(p = 0.031-2021 年与 2020 年相比,p = 0.011-2021 年与 2019 年相比),在此期间观察到肠内营养处方增加与 COVID-19 病例之间存在关系。高蛋白和高热量饮食疗法是有或没有糖尿病的患者最常开的处方。所有这些都给马德里社区带来了更高的成本。总之,COVID-19 显著影响了营养支持的处方,尤其是 75 岁以上人群。