Research Centre on Health, Quality of Life and Lifestyle in a Geodemographic and Socioeconomic Context (GeoQol), Department of Social Geography and Regional Development, Faculty of Science, Charles University, Albertov 6, 128 43 Prague, Czech Republic.
Nutrients. 2022 Sep 27;14(19):4001. doi: 10.3390/nu14194001.
Higher body mass index (BMI) has been associated with a higher risk for severe COVID-19 outcomes. The aim of this study was to investigate associations among BMI, underlying health conditions and hospital admission as well as the effects of COVID-19 vaccines in adults aged 50 years and older in Europe using data from the Survey of Health, Ageing and Retirement in Europe (SHARE) which was collected from June to August 2021, shortly after the second wave of the COVID-19 pandemic occurred in Europe. Survey data totalling 1936 individuals were used for statistical analyses to calculate the likelihood of hospitalization due to COVID-19 infection in relation to BMI, sociodemographic factors, comorbidities and COVID vaccination status. Approximately 16% of individuals testing positive for COVID-19 were hospitalized for COVID-19, and over 75% of these hospitalized individuals were either overweight or obese. The likelihood of hospitalization for individuals with obesity was approximately 1.5 times (CI [1.05-2.05]) higher than those with a healthy weight (BMI = 18.5-24.9 kg/m) after adjusting for BMI, sex and age. After adjusting for sociodemographic factors, vaccination and comorbidities, the likelihood of hospitalization for individuals with obesity was 1.34 times higher than those with a healthy weight (CI [0.94-1.90]). Vaccine uptake was lowest in individuals with obesity (BMI ≥ 30 kg/m) in all age groups. Individuals who had not received a vaccine were 1.8 times more likely to be hospitalized (CI [1.34-2.30]). Across European regions, obesity is associated with higher odds of hospitalization, and vaccination may be effective to reduce these odds for older adults.
更高的身体质量指数（BMI）与更严重的 COVID-19 结果风险增加有关。本研究旨在使用欧洲健康老龄化和退休调查（SHARE）的数据，调查 50 岁及以上成年人中 BMI、潜在健康状况和住院以及 COVID-19 疫苗的相关性，这些数据是在 COVID-19 大流行在欧洲发生第二波后于 2021 年 6 月至 8 月收集的。总共使用了 1936 名个体的调查数据进行统计分析，以计算与 BMI、社会人口因素、合并症和 COVID 疫苗接种状况相关的 COVID-19 感染住院的可能性。大约 16%的 COVID-19 检测呈阳性的个体因 COVID-19 住院，其中超过 75%的住院个体超重或肥胖。在调整 BMI、性别和年龄后，肥胖个体的住院可能性大约是健康体重（BMI=18.5-24.9kg/m）个体的 1.5 倍（CI[1.05-2.05]）。在调整社会人口因素、疫苗接种和合并症后，肥胖个体的住院可能性比健康体重个体高 1.34 倍（CI[0.94-1.90]）。所有年龄组中，肥胖个体（BMI≥30kg/m）的疫苗接种率最低。未接种疫苗的个体住院的可能性增加 1.8 倍（CI[1.34-2.30]）。在整个欧洲地区，肥胖与更高的住院几率相关，而疫苗接种可能对降低老年人的这些几率有效。
