University of Health Sciences, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Am J Surg. 2023 Feb;225(2):357-361. doi: 10.1016/j.amjsurg.2022.08.021. Epub 2022 Sep 1.
Patients with obesity are at a high risk of severe disease and death from Coronavirus Disease 2019 (COVID-19). Vaccination offers a safe and effective means of reducing this risk. The rate of COVID-19 vaccine refusal in patients with obesity is unknown.
Patients with obesity were administered validated questionnaires assessing COVID-19 fear, general vaccine hesitancy, and COVID-19-specific vaccine hesitancy.
507 participants completed the study. COVID-19 vaccine hesitancy was high: Fifteen percent of patients refused COVID-19 vaccine. Hesitancy related to other vaccines was also high: Eight percent of patients refused a vaccine in the past, and 15% delayed a vaccine. Fear of side effects and doubts regarding effectiveness were the most common reasons for vaccine refusal.
Despite high risk for complications, vaccine hesitancy is high among patients with obesity. Targeted public health interventions are critical to reduce vaccine hesitancy and improve vaccination rates.
肥胖患者患 2019 年冠状病毒病（COVID-19）重症和死亡的风险很高。接种疫苗是降低这种风险的安全有效手段。肥胖患者拒绝 COVID-19 疫苗的比例尚不清楚。
对肥胖患者进行了评估 COVID-19 恐惧、一般疫苗犹豫和 COVID-19 特定疫苗犹豫的有效问卷。
507 名参与者完成了这项研究。COVID-19 疫苗犹豫率很高：15%的患者拒绝接种 COVID-19 疫苗。对其他疫苗的犹豫也很高：过去 8%的患者拒绝接种疫苗，15%的患者推迟接种疫苗。对副作用的恐惧和对有效性的怀疑是拒绝接种疫苗的最常见原因。
尽管肥胖患者并发症风险高，但疫苗犹豫率仍然很高。需要采取有针对性的公共卫生干预措施来减少疫苗犹豫，提高接种率。
