Kurczewska Joanna
Faculty of Chemistry, Adam Mickiewicz University, 61-614 Poznan, Poland.
Polymers (Basel). 2022 Oct 6;14(19):4189. doi: 10.3390/polym14194189.
Polysaccharides constitute one of the most important families of biopolymers. Natural polysaccharide-based drug delivery systems are of constant interest to the scientific community due to their unique properties: biocompatibility, non-toxicity, biodegradability, and high availability. These promising biomaterials protect sensitive active agents and provide their controlled release in targeted sites. The application of natural polysaccharides as drug delivery systems is also intensively developed by Polish scientists. The present review focuses on case studies from the last few years authored or co-authored by research centers in Poland. A particular emphasis was placed on the diversity of the formulations in terms of the active substance carried, the drug delivery route, the composition of the material, and its preparation method.
多糖是生物聚合物中最重要的家族之一。基于天然多糖的药物递送系统因其独特的性质:生物相容性、无毒性、可生物降解性和高可得性,一直受到科学界的关注。这些有前景的生物材料可保护敏感的活性剂,并使其在靶向部位实现控释。波兰科学家也在大力开展将天然多糖用作药物递送系统的研究。本综述重点关注波兰研究中心在过去几年撰写或共同撰写的案例研究。特别强调了制剂在所载活性物质、药物递送途径、材料组成及其制备方法方面的多样性。