Kim Minji, Jee Won-Hee, Lee Youngjun, Hong Ji Hyun, Jung Chan Kwon, Chung Yang-Guk, Lee So-Yeon
Taehan Yongsang Uihakhoe Chi. 2022 Jan;83(1):112-126. doi: 10.3348/jksr.2021.0037. Epub 2021 Sep 16.
To determine the value of 3 Tesla (T) MRI texture analysis for predicting tumor margin infiltration in soft tissue sarcomas.
Thirty-one patients who underwent 3T MRI and had a pathologically confirmed diagnosis of soft tissue sarcoma were included in this study. Margin infiltration on pathology was used as the gold standard. Texture analysis of soft tissue sarcomas was performed on axial T1-weighted images (WI) and T2WI, fat-suppressed contrast-enhanced (CE) T1WI, diffusion-weighted images (DWI) with b-value of 800 s/mm, and apparent diffusion coefficient (ADC) was mapped. Quantitative parameters were compared between sarcomas with infiltrative margins and those with circumscribed margins.
Among the 31 patients with soft tissue sarcomas, 23 showed tumor margin infiltration on pathology. There were significant differences in kurtosis with the spatial scaling factor (SSF) of 0 and 6 on T1WI, kurtosis (SSF, 0) on CE-T1WI, skewness (SSF, 0) on DWI, and skewness (SSF, 2, 4) on ADC between sarcomas with infiltrative margins and those with circumscribed margins ( ≤ 0.046). The area under the receiver operating characteristic curve based on MR texture features for identification of infiltrative tumor margins was 0.951 ( < 0.001).
MR texture analysis is reliable and accurate for the prediction of infiltrative margins of soft tissue sarcomas.
确定3特斯拉（T）磁共振成像（MRI）纹理分析在预测软组织肉瘤肿瘤边缘浸润方面的价值。
本研究纳入了31例接受3T MRI检查且病理确诊为软组织肉瘤的患者。将病理上的边缘浸润作为金标准。对软组织肉瘤在轴位T1加权图像（WI）、T2WI、脂肪抑制对比增强（CE）T1WI、b值为800 s/mm²的扩散加权图像（DWI）上进行纹理分析，并绘制表观扩散系数（ADC）图。比较具有浸润性边缘的肉瘤和具有局限性边缘的肉瘤之间的定量参数。
在31例软组织肉瘤患者中，23例在病理上显示肿瘤边缘浸润。具有浸润性边缘的肉瘤和具有局限性边缘的肉瘤在T1WI上空间缩放因子（SSF）为0和6时的峰度、CE-T1WI上的峰度（SSF，0）、DWI上的偏度（SSF，0）以及ADC上的偏度（SSF，2，4）存在显著差异（P≤0.046）。基于MR纹理特征识别浸润性肿瘤边缘的受试者操作特征曲线下面积为0.951（P<0.001）。
MR纹理分析在预测软组织肉瘤浸润性边缘方面可靠且准确。
