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齐纳综合征:伴有骨转移的同侧肾缺如和精囊囊肿

Zinner Syndrome: Ipsilateral Renal Agenesis and Seminal Vesicle Cyst Presenting With Bony Metastasis.

作者信息

Deen Shameer, Arora Ajay, Lunawat Rahul

机构信息

Urology, Princess Royal University Hospital, London, GBR.

Radiodiagnosis, Kings College Hospital, London, GBR.

出版信息

Cureus. 2022 Sep 8;14(9):e28949. doi: 10.7759/cureus.28949. eCollection 2022 Sep.

Abstract

Zinner syndrome is a rare congenital triad of mesonephric duct abnormality encompassing unilateral renal agenesis or dysgenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. Literature has reported 214 cases, with the most common presentation being lower urinary tract symptoms and abdominal pain. Most cases are incidentally diagnosed, and MRI has been the choice of radiological diagnosis. We report the case of an 81-year-old male who presented with a three-month history of a fungating elbow lesion, elbow pain, and weight loss. Imaging revealed an ipsilateral seminal vesicle cyst, absent kidney, and ejaculatory duct obstruction, i.e., Zinner syndrome with bone metastasis. A bone biopsy revealed a urothelial primary, and cyst aspiration and cytology revealed spermatozoa and malignant cells representing an adenocarcinoma. This patient was managed with symptom control, radiotherapy to the elbow, and palliative chemotherapy, but later succumbed to the condition.

摘要

齐纳综合征是一种罕见的先天性中肾管异常三联征,包括单侧肾缺如或发育不全、同侧精囊囊肿和射精管梗阻。文献报道了214例病例,最常见的表现是下尿路症状和腹痛。大多数病例是偶然诊断出来的,磁共振成像(MRI)一直是放射学诊断的选择。我们报告了一例81岁男性患者,其出现了三个月的肘部溃疡性病变、肘部疼痛和体重减轻病史。影像学检查显示同侧精囊囊肿、肾脏缺如和射精管梗阻,即伴有骨转移的齐纳综合征。骨活检显示为尿路上皮原发肿瘤,囊肿抽吸和细胞学检查发现精子和代表腺癌的恶性细胞。该患者接受了症状控制、肘部放疗和姑息化疗,但后来病情恶化死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b8f/9547664/fd16e90ba11a/cureus-0014-00000028949-i01.jpg

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