Department of Psychiatry, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Integrated Medical Science, Florida Atlantic University FAU, Florida, USA.
BMC Geriatr. 2022 Oct 14;22(1):801. doi: 10.1186/s12877-022-03391-y.
For screening and distinguishing between mild neurocognitive disorder (mNCD) and normal cognitive age-related changes in primary care centers, a simple and practical tool is necessary. Therefore, this study aims to determine the validity and reliability of the Farsi version of the Ascertain Dementia 8-item (AD8-F) informant interview in patients with mNCD.
This is a study of the psychometric properties of the Farsi AD8. The participants include sixty informant-patient dyads with mNCD and sixty controls with normal cognition. The AD8 was compared to the mini-mental state examination (MMSE) and the Mini-Cog. As a gold standard, the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for mNCD was used. The reliability was measured using internal consistency and test-retest. Validity was assessed by evaluating the content, concurrent, and construct validity. Data were analyzed via Cronbach's α, Pearson correlation, independent t-test, and analysis of variance (ANOVA) and area under the curve (AUC) by statistical package for the social sciences (SPSS) v.23.
Cronbach's α was 0.71. Test-retest reproducibility was 0.8. The AD8 had inverse correlations with the Mini-Cog (r = - 0.70, P < 0.01) and MMSE (r = - 0.56, P < 0.01). The area under the curve was 0.88. The optimal cutoff score was > 2. Sensitivity and specificity were 80 and 83%, respectively. The positive predictive value was 83%. The negative predictive value was 81%.
Our results suggest that this tool can be used as a screening tool to detect a mild neurocognitive disorder in primary care centers.
在基层医疗中心，为了筛选和区分轻度神经认知障碍（mNCD）和正常认知相关变化，需要一种简单实用的工具。因此，本研究旨在确定 Farsi 版 Ascertain Dementia 8-item（AD8-F）知情者访谈在 mNCD 患者中的有效性和可靠性。
这是一项关于 Farsi AD8 的心理测量特性的研究。参与者包括 60 名 mNCD 患者和 60 名认知正常的对照者及其家属。将 AD8 与简易精神状态检查（MMSE）和 Mini-Cog 进行比较。以《精神障碍诊断与统计手册》第五版（DSM-5）mNCD 标准为金标准。采用内部一致性和重测信度来测量可靠性。通过评估内容、同时和结构效度来评估有效性。数据采用社会科学统计软件包（SPSS）v.23 的 Cronbach's α、Pearson 相关、独立 t 检验、方差分析（ANOVA）和曲线下面积（AUC）进行分析。
Cronbach's α 为 0.71。重测信度为 0.8。AD8 与 Mini-Cog（r = -0.70，P < 0.01）和 MMSE（r = -0.56，P < 0.01）呈负相关。曲线下面积为 0.88。最佳截断值>2。灵敏度和特异度分别为 80%和 83%。阳性预测值为 83%。阴性预测值为 81%。
我们的结果表明，该工具可用于基层医疗中心筛查轻度神经认知障碍。
