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AD8(痴呆筛查访谈)是一种有效且可靠的筛查量表,不仅可用于痴呆症,也可用于土耳其老年门诊患者的轻度认知障碍。

The AD8 (Dementia Screening Interview) is a valid and reliable screening scale not only for dementia but also for mild cognitive impairment in the Turkish geriatric outpatients.

机构信息

Unit for Aging Brain and Dementia,Department of Geriatric Medicine,Dokuz Eylul University,Faculty of Medicine,Izmir,Turkey.

Department of Geriatric Medicine,Dokuz Eylul University,Faculty of Medicine,Izmir,Turkey.

出版信息

Int Psychogeriatr. 2019 Feb;31(2):223-229. doi: 10.1017/S1041610218000674. Epub 2018 Jun 20.

Abstract

UNLABELLED

ABSTRACTIntroduction:There is still a need for short, practical, and daily-appropriate scales to distinguish between normal cognitive aging, mild cognitive impairment (MCI), or dementia for patients with memory complaints. This study aimed to determine validity and reliability of AD8 (Dementia Screening Interview) to detect both MCI and dementia in Turkish geriatric outpatients.

METHODS

Comprehensive geriatric assessment was performed in 334 patients, who attended with their informants to the geriatric outpatient clinic for memory complaints. In addition to the AD8, they were screened using Clinical Dementia Rating scale (CDR) and Mini-Mental State Examination. The diagnosis of dementia and MCI was made according to the Diagnostic and Statistical Manual of Mental Disorders - fifth edition (DSM-5) criteria.

RESULTS

The mean age of the patients was 74.5±8.5. Of them, 156 were considered as non-cognitive impairment, 60 as MCI, and 118 as dementia. Cronbach's α value of the AD8 was 0.928. The total AD8 scores were found to be negatively correlated with the MMSE scores (r = -0.801), and positively correlated with CDR score (r = 0.879) (p < 0.001, for each). The area under the receiver-operating characteristics curve was 0.979 for cognitive impairment, and 0.999 for dementia. We found that AD8 can show dementia and MCI when the cut-off values are ≥5 and 3-4, respectively, with a sensitivity of 100% and 81.67% and specificity of 96.3% and 93.59%.

CONCLUSION

AD8 is one of the fast, simple, and sensitive screening methods for detecting both minor and major cognitive impairments. With regard to these features, it can be used in older adults attending the primary care settings with memory complaints.

摘要

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摘要

背景

对于有记忆主诉的患者,仍需要一种简短、实用且适合日常应用的量表来区分正常认知老化、轻度认知障碍(MCI)或痴呆。本研究旨在确定 AD8(痴呆筛查访谈)用于检测土耳其老年门诊患者 MCI 和痴呆的有效性和可靠性。

方法

对 334 名因记忆主诉就诊老年门诊的患者及其家属进行全面的老年评估。除 AD8 外,他们还使用临床痴呆评定量表(CDR)和简易精神状态检查(MMSE)进行筛查。根据《精神障碍诊断与统计手册-第五版》(DSM-5)标准诊断痴呆和 MCI。

结果

患者的平均年龄为 74.5±8.5 岁。其中,156 例被认为是非认知障碍,60 例为 MCI,118 例为痴呆。AD8 的克朗巴赫α值为 0.928。AD8 的总分与 MMSE 评分呈负相关(r = -0.801),与 CDR 评分呈正相关(r = 0.879)(p < 0.001,均为)。接受者操作特征曲线下的面积为认知障碍 0.979,痴呆 0.999。我们发现,当截断值分别为≥5 和 3-4 时,AD8 可以显示痴呆和 MCI,其敏感性分别为 100%和 81.67%,特异性分别为 96.3%和 93.59%。

结论

AD8 是一种快速、简单、敏感的筛查方法,可用于检测轻度和重度认知障碍。鉴于这些特点,它可用于记忆主诉就诊于初级保健机构的老年人。

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