Borggrefe M, Budde T, Podczeck A, Breithardt G
J Am Coll Cardiol. 1987 Sep;10(3):576-82. doi: 10.1016/s0735-1097(87)80200-0.
High frequency alternating current ablation of an accessory pathway was performed in a patient with incessant circus movement tachycardia using a right-sided, free wall accessory pathway. Antiarrhythmic drugs, antitachycardia pacing and transvenous catheter ablation using high energy direct current shocks could not control the supraventricular tachycardia. A 7F bipolar electrode catheter with an interelectrode distance of 1.2 cm was positioned at the site of earliest retrograde activation during circus movement tachycardia. At this area, two alternating current high frequency impulses were delivered with an energy output of 50 W through the distal tip of the bipolar catheter, while the patient was awake. After the first shock supraventricular tachycardia terminated and accessory pathway conduction was absent without altering anterograde conduction in the normal atrioventricular (AV) conduction system. No reports of pain or other complications were noted. In short-term follow-up of 5 months, the patient had been free of arrhythmias without antiarrhythmic medication. Thus, high frequency alternating current ablation was performed for the first time in the treatment of an arrhythmia incorporating an accessory pathway in a human. This technique may be an attractive alternative to the available transcatheter ablation techniques and to antitachycardia surgery.
在一名患有持续性折返性心动过速且存在右侧游离壁旁道的患者中,使用高频交流电对旁道进行了消融。抗心律失常药物、抗心动过速起搏以及使用高能直流电电击的经静脉导管消融均无法控制室上性心动过速。将一根电极间距为1.2厘米的7F双极电极导管置于折返性心动过速期间最早逆行激动的部位。在此区域,在患者清醒状态下,通过双极导管的远端尖端以50瓦的能量输出施加两个高频交流电脉冲。首次电击后,室上性心动过速终止,旁道传导消失,而正常房室传导系统的前向传导未改变。未观察到疼痛或其他并发症的报告。在5个月的短期随访中,患者未服用抗心律失常药物,未发生心律失常。因此,高频交流电消融首次用于治疗人类合并旁道的心律失常。该技术可能是现有经导管消融技术和抗心动过速手术的一种有吸引力的替代方法。