Huang Risheng, Li Zhijia, Weng Shanshan, Wu Shenghao
Department of Thoracic Surgery, The Dingli Clinical College of Wenzhou Medical University (The Second Affiliated Hospital of Shanghai University, Wenzhou Central Hospital), Wenzhou City, Zhejiang Province, China.
Department of Urology Surgery, The Dingli Clinical College of Wenzhou Medical University (The Second Affiliated Hospital of Shanghai University, Wenzhou Central Hospital), Wenzhou City, Zhejiang Province, China.
Open Life Sci. 2022 Sep 26;17(1):1263-1268. doi: 10.1515/biol-2022-0500. eCollection 2022.
Multiple primary malignancies (MPMs) are defined as the coexistence of at least two unrelated primary malignancies in a single patient, with the tumors differing in their histology. MPMs in the same patient, when present within 6 months of the primary tumor diagnosis, are considered a synchronous occurrence. In this case report, we describe a 61-year-old man who presented with three distinct tumors concurrently in 2021: noninvasive urothelial carcinoma of the bladder, diffuse large B-cell lymphoma, and squamous cell carcinoma of the lung. We discuss the process of therapy and briefly review the literature. MPMs are increasing in incidence, requiring an interdisciplinary approach to diagnosis and treatment.
多原发性恶性肿瘤（MPMs）被定义为同一患者体内至少存在两种不相关的原发性恶性肿瘤，且肿瘤的组织学类型不同。同一患者的MPMs，如果在原发性肿瘤诊断后的6个月内出现，则被认为是同时发生。在本病例报告中，我们描述了一名61岁男性，他在2021年同时出现了三种不同的肿瘤：膀胱非浸润性尿路上皮癌、弥漫性大B细胞淋巴瘤和肺鳞状细胞癌。我们讨论了治疗过程并简要回顾了文献。MPMs的发病率正在上升，需要采用跨学科方法进行诊断和治疗。
