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用于磁性内窥镜活检的机器人自主系统

Robotic Autonomy for Magnetic Endoscope Biopsy.

作者信息

Martin James W, Barducci Lavinia, Scaglioni Bruno, Norton Joseph C, Winters Conchubhair, Subramanian Venkataraman, Arezzo Alberto, Obstein Keith L, Valdastri Pietro

机构信息

STORM Lab UK, University of Leeds, Leeds, UK.

Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, UK.

出版信息

IEEE Trans Med Robot Bionics. 2022 Aug;4(3):599-607. doi: 10.1109/TMRB.2022.3187028. Epub 2022 Jun 29.

DOI:10.1109/TMRB.2022.3187028
PMID:36249558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9555223/
Abstract

Magnetically actuated endoscopes are currently transitioning in to clinical use for procedures such as colonoscopy, presenting numerous benefits over their conventional counterparts. Intelligent and easy-to-use control strategies are an essential part of their clinical effectiveness due to the un-intuitive nature of magnetic field interaction. However, work on developing intelligent control for these devices has mainly been focused on general purpose endoscope navigation. In this work, we investigate the use of autonomous robotic control for magnetic colonoscope intervention via biopsy, another major component of clinical viability. We have developed control strategies with varying levels of robotic autonomy, including semi-autonomous routines for identifying and performing targeted biopsy, as well as random quadrant biopsy. We present and compare the performance of these approaches to magnetic endoscope biopsy against the use of a standard flexible endoscope on bench-top using a colonoscopy training simulator and silicone colon model. The semi-autonomous routines for targeted and random quadrant biopsy were shown to reduce user workload with comparable times to using a standard flexible endoscope.

摘要

磁驱动内窥镜目前正逐渐过渡到临床应用,用于结肠镜检查等程序,与传统内窥镜相比具有诸多优势。由于磁场相互作用的性质不直观,智能且易于使用的控制策略是其临床有效性的重要组成部分。然而,针对这些设备开发智能控制的工作主要集中在通用内窥镜导航上。在这项工作中,我们研究了通过活检对磁控结肠镜进行自主机器人控制的应用,活检是临床可行性的另一个主要组成部分。我们已经开发了具有不同程度机器人自主性的控制策略,包括用于识别和进行靶向活检的半自主程序以及随机象限活检。我们使用结肠镜检查训练模拟器和硅胶结肠模型,在实验台上展示并比较了这些磁内窥镜活检方法与使用标准柔性内窥镜的性能。结果表明,靶向和随机象限活检的半自主程序在与使用标准柔性内窥镜相当的时间内减少了用户工作量。

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Automatic lumen detection and magnetic alignment control for magnetic-assisted capsule colonoscope system optimization.自动管腔检测和磁控对齐控制,用于优化磁辅助胶囊结肠内窥镜系统。
Sci Rep. 2021 Mar 19;11(1):6460. doi: 10.1038/s41598-021-86101-9.
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Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19.2019冠状病毒病疫情期间机器人辅助柔性内镜检查指南
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Enabling Autonomous Colonoscopy Intervention Using a Robotic Endoscope Platform.使用机器人内窥镜平台实现自主结肠镜检查干预。
IEEE Trans Biomed Eng. 2021 Jun;68(6):1957-1968. doi: 10.1109/TBME.2020.3043388. Epub 2021 May 21.
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Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation.通过智能自主磁操控开启结肠镜检查的未来。
Nat Mach Intell. 2020 Oct;2(10):595-606. doi: 10.1038/s42256-020-00231-9. Epub 2020 Oct 12.
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Robotic-Assisted Colonoscopy Platform with a Magnetically-Actuated Soft-Tethered Capsule.具有磁驱动软系留胶囊的机器人辅助结肠镜检查平台。
Cancers (Basel). 2020 Sep 2;12(9):2485. doi: 10.3390/cancers12092485.
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Real-time detection of colon polyps during colonoscopy using deep learning: systematic validation with four independent datasets.利用深度学习技术在结肠镜检查中实时检测结肠息肉:四项独立数据集的系统验证。
Sci Rep. 2020 May 20;10(1):8379. doi: 10.1038/s41598-020-65387-1.
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The hidden cost of colonoscopy including cost of reprocessing and infection rate: the implications for disposable colonoscopes.结肠镜检查的隐性成本,包括再处理成本和感染率:对一次性结肠镜的影响。
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