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用8-甲氧基补骨脂素和阳光治疗银屑病。

Treatment of psoriasis with 8-methoxypsoralen and sunlight.

作者信息

Robertson D B, McCarty J R, Jarratt M

出版信息

South Med J. 1978 Nov;71(11):1345-9. doi: 10.1097/00007611-197811000-00009.

DOI:10.1097/00007611-197811000-00009
PMID:362536
Abstract

Photochemotherapy with 8-methoxypsoralen and sunlight (PUVA-SOL), administered three times weekly, proved effective in the treatment of psoriasis. Weekend photochemotherapy (modified PUVA-SOL) also appeared useful as an adjunct to standard topical corticosteroid therapy. Careful measurement of ambient long-wave ultraviolet light (UVA) in the treatment locale and respect for the phototoxic potential of PUVA-SOL are necessary for success. The long-range toxicity of psoralen photochemotherapy remains undetermined.

摘要

每周三次给予8-甲氧基补骨脂素和阳光进行光化学疗法(PUVA-SOL),已证明对治疗银屑病有效。周末光化学疗法(改良PUVA-SOL)作为标准外用皮质类固醇疗法的辅助手段似乎也有用。为取得成功,必须仔细测量治疗场所的环境长波紫外线(UVA)并重视PUVA-SOL的光毒性潜力。补骨脂素光化学疗法的长期毒性仍未确定。

相似文献

1
Treatment of psoriasis with 8-methoxypsoralen and sunlight.用8-甲氧基补骨脂素和阳光治疗银屑病。
South Med J. 1978 Nov;71(11):1345-9. doi: 10.1097/00007611-197811000-00009.
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Photochemotherapy of psoriasis using methoxsalen and sunlight. A controlled study.
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[Double-blind studies on the effect of topical PUVA therapy for psoriasis. Supplement: open controlled studies on the effect of topical PUVA and topical steroid therapy for psoriasis. (author's transl)].[外用补骨脂素加长波紫外线光化学疗法治疗银屑病效果的双盲研究。补充:外用补骨脂素加长波紫外线光化学疗法与外用类固醇疗法治疗银屑病效果的开放对照研究。(作者译)]
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J Eur Acad Dermatol Venereol. 2012 May;26 Suppl 3:11-21. doi: 10.1111/j.1468-3083.2012.04519.x.
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Photochemotherapy for psoriasis. A clinical cooperative study of PUVA-48 and PUVA-64.银屑病的光化学疗法。PUVA - 48和PUVA - 64的临床合作研究。
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Photochemotherapy of psoriasis with methoxsalen and longwave ultraviolet light (PUVA).用甲氧沙林和长波紫外线(PUVA)对银屑病进行光化学疗法。
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Photochemotherapy (PUVA) and psoriasis: comparison of 8-MOP and 8-MOP/5-MOP.光化学疗法(补骨脂素加紫外线A,PUVA)与银屑病:8-甲氧基补骨脂素和8-甲氧基补骨脂素/5-甲氧基补骨脂素的比较
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Br J Dermatol. 1983 May;108(5):519-24. doi: 10.1111/j.1365-2133.1983.tb01051.x.

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