Verma Sanam, Graham Michelle M, Lecamwasam Ashani, Romanovsky Adam, Duggan Shelley, Bagshaw Sean, Senaratne Janek Manoj
Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada.
Department of Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada.
CJC Open. 2022 Jul 16;4(10):873-885. doi: 10.1016/j.cjco.2022.06.011. eCollection 2022 Oct.
A complex interaction occurs between cardiac and renal function. They are intricately tied together, and a range of disorders in both the heart and kidneys can alter the function of the other. The pathophysiology is complex, and these conditions are termed cardiorenal syndromes. They can be acute and/or chronic in nature, they result in and from hemodynamic consequences, systemic congestion, and metabolic abnormalities, and they lead to dysfunction of both the heart and kidneys. The aim of this article is to provide a review for cardiologists and intensivists who are treating patients for whom cardiac and renal interactions may complicate their picture. We review acute kidney injuries, management of the complications of renal dysfunction, renal replacement therapy, and cardiorenal syndromes.
心脏功能和肾脏功能之间存在复杂的相互作用。它们紧密相连,心脏和肾脏的一系列疾病都可能改变对方的功能。其病理生理学很复杂,这些病症被称为心肾综合征。它们在性质上可以是急性和/或慢性的,由血流动力学后果、全身充血和代谢异常引起并导致这些情况,进而导致心脏和肾脏功能障碍。本文旨在为治疗心脏和肾脏相互作用可能使病情复杂化的患者的心脏病专家和重症监护医生提供一篇综述。我们回顾了急性肾损伤、肾功能不全并发症的管理、肾脏替代治疗以及心肾综合征。