Appl Opt. 2022 Jul 20;61(21):6257-6267. doi: 10.1364/AO.458175.
This study proposed an unclad optical fiber biosensor based on the localized surface plasmon resonance phenomenon and operating at 650 nm using COMSOL Multiphysics 5.1 finite element method (FEM). Gold nanoparticles (50 nm thickness) were coated on the middle portion of the unclad fiber. Air, water, blood plasma, liver tissue, colon tissue, and pentanol (C5H11OH) were used as analytical layers with 3 µm. The sensor serves as a theoretical foundation for experimental research. The blood plasma had the highest sensitivity with a sensitivity of 10,638.297 nm/RIU and a resolution of 9.410-6RIU. The proposed sensor is a promising candidate for a low-cost, simple-geometry biochemical sensing solution.
本研究提出了一种基于局域表面等离子体共振现象的无覆层光纤生物传感器，工作波长为 650nm，使用 COMSOL Multiphysics 5.1 有限元方法（FEM）。在无覆层光纤的中部涂覆了金纳米粒子（50nm 厚）。空气、水、血桨、肝组织、结肠组织和戊醇（C5H11OH）作为分析层，厚度为 3µm。该传感器为实验研究提供了理论基础。血桨的灵敏度最高，灵敏度为 10,638.297nm/RIU，分辨率为 9.410-6RIU。该传感器是一种低成本、简单几何形状的生化传感解决方案的有前途的候选方案。
