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铜绿假单胞菌成为病原体的原因是什么?

What Makes Pseudomonas aeruginosa a Pathogen?

机构信息

Clinical Research Group, Department for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research, Hannover Medical School, Hannover, Germany.

出版信息

Adv Exp Med Biol. 2022;1386:283-301. doi: 10.1007/978-3-031-08491-1_10.

DOI:10.1007/978-3-031-08491-1_10
PMID:36258076
Abstract

Pseudomonas aeruginosa is classified as an opportunistic pathogen that causes a wide range of infections in humans, involving nearly all body systems, that vary from local to systemic and from self-limiting to life-threatening. This chapter outlines the features that have made P. aeruginosa a human pathogen. Each section starts with the argument in the heading followed by the epidemiological and/or experimental supportive evidence.

摘要

铜绿假单胞菌被归类为机会性病原体,可导致人类发生广泛的感染,涉及几乎所有的身体系统,从局部到全身,从轻症自限性到危及生命。本章概述了使铜绿假单胞菌成为人类病原体的特征。每个部分都以标题中的论点开头,然后是流行病学和/或实验支持证据。

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PLoS Pathog. 2021 Jun 23;17(6):e1009681. doi: 10.1371/journal.ppat.1009681. eCollection 2021 Jun.
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Compensatory evolution of Pseudomonas aeruginosa's slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis.铜绿假单胞菌生长缓慢表型的补偿进化提示了囊性纤维化适应机制。
Nat Commun. 2021 May 27;12(1):3186. doi: 10.1038/s41467-021-23451-y.
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