Department of Radiology, University of California San Diego, La Jolla, California, USA.
Research Service, Veterans Affairs San Diego Healthcare System, San Diego, California, USA.
NMR Biomed. 2023 Feb;36(2):e4843. doi: 10.1002/nbm.4843. Epub 2022 Nov 20.
Osteoarthritis is a common chronic degenerative disease that causes pain and disability with increasing incidence worldwide. The osteochondral junction is a dynamic region of the joint that is associated with the early development and progression of osteoarthritis. Despite the substantial advances achieved in the imaging of cartilage and application to osteoarthritis in recent years, the osteochondral junction has received limited attention. This is primarily related to technical limitations encountered with conventional MR sequences that are relatively insensitive to short T2 tissues and the rapid signal decay that characterizes these tissues. MR sequences with ultrashort echo time (UTE) are of great interest because they can provide images of high resolution and contrast in this region. Here, we briefly review the anatomy and function of cartilage, focusing on the osteochondral junction. We also review basic concepts and recent applications of UTE MR sequences focusing on the osteochondral junction.
骨关节炎是一种常见的慢性退行性疾病,随着全球发病率的增加,它会引起疼痛和残疾。软骨骨连接处是关节的一个活跃区域,与骨关节炎的早期发展和进展有关。尽管近年来在软骨成像和应用于骨关节炎方面取得了重大进展,但软骨骨连接处受到的关注有限。这主要与常规 MR 序列遇到的技术限制有关,这些序列对短 T2 组织相对不敏感,而这些组织的信号衰减很快。超短回波时间(UTE)MR 序列引起了极大的兴趣,因为它们可以在该区域提供高分辨率和对比度的图像。在这里,我们简要回顾了软骨的解剖结构和功能,重点介绍了软骨骨连接处。我们还回顾了 UTE MR 序列的基本概念和最新应用,重点介绍了软骨骨连接处。