Bezmialem Vakıf University School of Medicine, Department of Psychiatry, Istanbul, Turkey.
Marmara University School of Medicine, Department of Psychiatry, Istanbul, Turkey.
Psychiatry Res. 2022 Nov;317:114872. doi: 10.1016/j.psychres.2022.114872. Epub 2022 Oct 1.
Adverse childhood experiences create vulnerability to psychosis through biological and cognitive changes, and that may be observed as an increased emotional and psychotic response to daily life experiences in adulthood. This study aims to examine the effects of childhood maltreatment on psychotic patients' daily stress and emotional and psychotic intensity related to various experiences throughout the day. Daily activities and events, and emotional and psychotic intensity of forty-one psychotic patients were assessed with the Experience Sampling Method. The Childhood Trauma Questionnaire (CTQ) was used to evaluate childhood adversities. Multilevel regression analyses showed that all trauma subtypes, except for sexual abuse, were associated with increased psychosis and event-stress. Emotional maltreatment was the most associated trauma type with high negative and low positive affect and increased daily stress. Patients reported the highest stress and negative affect related to internal experiences but the lowest stress related to recreational actions. Social activities were also associated with higher positive affect and lower stress and psychosis, with the high CTQ group having greater stress in those activities. Our study demonstrates the negative impact of childhood trauma, especially emotional maltreatment, on daily stress and emotional and psychotic intensity in psychotic patients via different daily experiences.
不良的童年经历会通过生物和认知变化导致精神分裂症易感性,并且在成年后可能会表现为对日常生活经历的情绪和精神分裂症反应增强。本研究旨在探讨儿童期虐待对精神分裂症患者日常压力以及与全天各种经历相关的情绪和精神分裂症强度的影响。采用经验抽样法评估四十一例精神分裂症患者的日常活动和事件以及情绪和精神分裂症强度。使用童年创伤问卷(CTQ)评估儿童期逆境。多水平回归分析显示,除了性虐待之外,所有创伤亚型都与精神分裂症和事件压力增加有关。情感虐待是与高负性和低正性情绪以及增加的日常压力最相关的创伤类型。患者报告与内部体验相关的最高压力和负性情绪,但与娱乐活动相关的压力最低。社交活动也与更高的正性情绪和更低的压力和精神分裂症相关,高 CTQ 组在这些活动中压力更大。我们的研究表明,童年创伤,特别是情感虐待,通过不同的日常经历对精神分裂症患者的日常压力、情绪和精神分裂症强度产生负面影响。