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当前肝切除、肝移植及胰十二指肠切除术加速康复外科(ERAS)指南综述。

A review of the current ERAS guidelines for liver resection, liver transplantation and pancreatoduodenectomy.

作者信息

Bayramov N, Mammadova Sh

机构信息

Department of General Surgery and Transplantology, Azerbaijan Medical University, Baku, Azerbaijan.

出版信息

Ann Med Surg (Lond). 2022 Sep 8;82:104596. doi: 10.1016/j.amsu.2022.104596. eCollection 2022 Oct.

Abstract

In perioperative care after liver resection, transplantation and pancreatoduodenectomy, ERAS (Enhanced Recovery After Surgery) recommendations are based on the reducing invasiveness of procedures and the severity of the surgical stress, which results in decreasing complications and enhanced recovery. Recommendations for all three operations can be classified into five groups: recommended for all patients, recommended for special patient groups, rejected for all patients controversial recommendations, specific recommendations for all three operations. Preoperative counselling and psychological support, nutritional support, smoking and alcohol cessation, pre- and intraoperative antibiotic prophylaxis, thrombosis prevention, limiting of preoperative hunger and thirst to 4 and 6 h, preoperative intaking carbohydrate rich drink, alcohol-based antiseptics for skin preparation, a goal-directed infusion therapy, providing normothermia, early removal of the drainage tube glycemic control, dual antiemetic therapy, multimodal analgesia strategies, early oral feeding and activation, audit recommend for all patients. Postoperative antibiotic prophylaxis, enteral and parenteral nutrition, short-acting anxiolytics are recommended for individual patients. It is recommended to avoid Mercedes type incision, use of long-acting anxiolytics and postoperative nasogastric tube. The benefits of preoperative physical exercise, immunonutrition and probiotics are controversial. There are no specific recommendations for thoracic epidural anesthesia, preventing delayed gastric emptying and intestinal paresis in liver surgery.

摘要

在肝切除、肝移植及胰十二指肠切除术后的围手术期护理中,加速康复外科(ERAS,即术后快速康复)建议基于手术侵入性的降低及手术应激的严重程度,这会减少并发症并促进康复。这三种手术的建议可分为五类:适用于所有患者、适用于特殊患者群体、不适用于所有患者、有争议的建议、针对这三种手术的特定建议。术前咨询与心理支持、营养支持、戒烟戒酒、围手术期抗生素预防、血栓预防、将术前禁食禁水时间限制在4小时和6小时、术前摄入富含碳水化合物的饮品、使用酒精类防腐剂进行皮肤准备、目标导向性液体治疗、维持正常体温、早期拔除引流管、血糖控制、双重抗呕吐治疗、多模式镇痛策略、早期经口进食与活动、审核,这些适用于所有患者。术后抗生素预防、肠内和肠外营养、短效抗焦虑药适用于个别患者。建议避免采用梅赛德斯式切口、使用长效抗焦虑药及术后留置鼻胃管。术前体育锻炼、免疫营养和益生菌的益处存在争议。对于胸段硬膜外麻醉、预防肝手术中胃排空延迟和肠麻痹,尚无特定建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dc9/9577502/f073d9384fb7/gr1.jpg

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