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通过用于可穿戴医疗监测系统的冗余去噪独立成分分析方法减少心电图信号中的运动伪影:算法开发与验证

Motion Artifact Reduction in Electrocardiogram Signals Through a Redundant Denoising Independent Component Analysis Method for Wearable Health Care Monitoring Systems: Algorithm Development and Validation.

作者信息

Castaño Usuga Fabian Andres, Gissel Christian, Hernández Alher Mauricio

机构信息

Bioinstrumentation and Clinical Engineering Research Group, Bioengineering Department, Engineering Faculty, Universidad de Antioquia, Medellín, Colombia.

Department of Health Economics, Justus Liebig University Giessen, Giessen, Germany.

出版信息

JMIR Med Inform. 2022 Nov 25;10(11):e40826. doi: 10.2196/40826.

Abstract

BACKGROUND

The quest for improved diagnosis and treatment in home health care models has led to the development of wearable medical devices for remote vital signs monitoring. An accurate signal and a high diagnostic yield are critical for the cost-effectiveness of wearable health care monitoring systems and their widespread application in resource-constrained environments. Despite technological advances, the information acquired by these devices can be contaminated by motion artifacts (MA) leading to misdiagnosis or repeated procedures with increases in associated costs. This makes it necessary to develop methods to improve the quality of the signal acquired by these devices.

OBJECTIVE

We aimed to present a novel method for electrocardiogram (ECG) signal denoising to reduce MA. We aimed to analyze the method's performance and to compare its performance to that of existing approaches.

METHODS

We present the novel Redundant denoising Independent Component Analysis method for ECG signal denoising based on the redundant and simultaneous acquisition of ECG signals and movement information, multichannel processing, and performance assessment considering the information contained in the signal waveform. The method is based on data including ECG signals from the patient's chest and back, the acquisition of triaxial movement signals from inertial measurement units, a reference signal synthesized from an autoregressive model, and the separation of interest and noise sources through multichannel independent component analysis.

RESULTS

The proposed method significantly reduced MA, showing better performance and introducing a smaller distortion in the interest signal compared with other methods. Finally, the performance of the proposed method was compared to that of wavelet shrinkage and wavelet independent component analysis through the assessment of signal-to-noise ratio, dynamic time warping, and a proposed index based on the signal waveform evaluation with an ensemble average ECG.

CONCLUSIONS

Our novel ECG denoising method is a contribution to converting wearable devices into medical monitoring tools that can be used to support the remote diagnosis and monitoring of cardiovascular diseases. A more accurate signal substantially improves the diagnostic yield of wearable devices. A better yield improves the devices' cost-effectiveness and contributes to their widespread application.

摘要

背景

在家庭医疗保健模式中,对改善诊断和治疗的追求促使了用于远程生命体征监测的可穿戴医疗设备的发展。准确的信号和高诊断率对于可穿戴医疗保健监测系统的成本效益及其在资源有限环境中的广泛应用至关重要。尽管技术取得了进步,但这些设备获取的信息可能会受到运动伪影(MA)的干扰,导致误诊或重复操作,从而增加相关成本。这使得有必要开发方法来提高这些设备获取信号的质量。

目的

我们旨在提出一种用于心电图(ECG)信号去噪以减少运动伪影的新方法。我们旨在分析该方法的性能,并将其性能与现有方法进行比较。

方法

我们提出了一种新颖的冗余去噪独立分量分析方法用于ECG信号去噪,该方法基于ECG信号和运动信息的冗余同时采集、多通道处理以及考虑信号波形中所含信息的性能评估。该方法基于包括来自患者胸部和背部的ECG信号、来自惯性测量单元的三轴运动信号的采集、从自回归模型合成的参考信号,以及通过多通道独立分量分析分离感兴趣源和噪声源的数据。

结果

与其他方法相比,所提出的方法显著减少了运动伪影,表现出更好的性能,并且在感兴趣信号中引入的失真更小。最后,通过评估信噪比、动态时间规整以及基于整体平均心电图的信号波形评估所提出的指标,将所提出方法的性能与小波收缩和小波独立分量分析的性能进行了比较。

结论

我们新颖的ECG去噪方法有助于将可穿戴设备转变为可用于支持心血管疾病远程诊断和监测的医疗监测工具。更准确的信号可大幅提高可穿戴设备的诊断率。更高的诊断率可提高设备的成本效益,并有助于其广泛应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b05/9736764/f5e4da166a4e/medinform_v10i11e40826_fig1.jpg

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